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Related Concept Videos

Salivary Glands and Saliva01:23

Salivary Glands and Saliva

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The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
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Exocrine Glands: Unicellular and Multicellular Glands01:29

Exocrine Glands: Unicellular and Multicellular Glands

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Exocrine glands are classified as unicellular and multicellular. The unicellular glands are scattered single cells, such as goblet cells, found in the mucous membranes of the small and large intestines. On the other hand, multicellular exocrine glands develop as secretory sheets, like the internal lining of the abdomen or chest. Such secretory sheets release their secretions directly into the lumen of these organs. In addition, some multicellular glands have deep-seated secretory units to...
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The Pituitary Gland01:17

The Pituitary Gland

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The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
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The Parathyroid Glands00:59

The Parathyroid Glands

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The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
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The Pineal Gland01:02

The Pineal Gland

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The pineal gland, a diminutive endocrine structure named for its pinecone-shaped appearance, is situated atop the third ventricle within the diencephalon region of the forebrain. This gland, composed of secretory cells known as pinealocytes arranged in compact cords and clusters around dense particles of calcium salts, plays a pivotal role in hormonal regulation.
The primary secretion of the pineal gland is the hormone melatonin, derived from serotonin. The concentration of melatonin in the...
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The Mammary Glands01:12

The Mammary Glands

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The female breast is a hemispheric projection of variable size positioned anterior to the pectoralis major and serratus anterior muscles. A fascia layer composed of dense, irregular connective tissue connects it to these muscles.
Each breast features a pigmented projection known as the nipple, through which milk emerges via closely spaced openings of ducts, referred to as lactiferous ducts. Surrounding the nipple is a circular pigmented area of skin named the areola, which appears rough due to...
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Updated: Feb 2, 2026

Dissection of Midgut and Salivary Glands from Ae. aegypti Mosquitoes
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Salivary Gland Malignancies.

Eric R Carlson1, Thomas Schlieve2

  • 1Department of Oral and Maxillofacial Surgery, University of Tennessee Cancer Institute, 1930 Alcoa Highway, Suite 335, Knoxville, TN 37920, USA.

Oral and Maxillofacial Surgery Clinics of North America
|November 20, 2018
PubMed
Summary

Malignant salivary gland tumors are rare and diverse head and neck cancers. This review covers their epidemiology, pathology, and recommended treatments for better patient outcomes.

Keywords:
Buccal mucosaLipPalateParotid glandSublingual glandSubmandibular gland

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Area of Science:

  • Oncology
  • Pathology
  • Head and Neck Surgery

Background:

  • Salivary gland tumors are rare, heterogeneous neoplasms originating from major and minor salivary glands.
  • Malignant salivary gland tumors affect both adult and pediatric populations.
  • Accurate diagnosis and treatment present significant challenges for clinicians.

Purpose of the Study:

  • To review the epidemiology and pathology of malignant salivary gland tumors.
  • To provide evidence-based recommendations for optimal treatment strategies.
  • To enhance understanding and management of these rare cancers.

Main Methods:

  • Comprehensive literature review of epidemiological data.
  • Analysis of pathological classifications and characteristics.
  • Synthesis of current treatment guidelines and outcomes.

Main Results:

  • Malignant salivary gland tumors exhibit diverse cell types and wide incidence distribution.
  • Pathological heterogeneity complicates diagnosis and treatment planning.
  • Multidisciplinary approaches are crucial for successful management.

Conclusions:

  • Understanding the epidemiology and pathology is key to diagnosing malignant salivary gland tumors.
  • Tailored treatment strategies based on tumor type and stage are essential.
  • Further research can improve outcomes for patients with these rare malignancies.