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06:34
Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
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Association between Fragmented QRS and Left Ventricular Systolic Function in Patients with Erectile Dysfunction
Osman Bektaş1, Ahmet Karagöz2, Adil Bayramoğlu1
1Department of Cardiology, Ordu University, Ordu.
Acta Cardiologica Sinica
|November 20, 2018
Summary
Fragmented QRS (fQRS) is more common in men with erectile dysfunction (ED), indicating potential subclinical left ventricular (LV) systolic dysfunction even without coronary artery disease.
Area of Science:
- Cardiology
- Electrophysiology
- Men's Health
Background:
- Erectile dysfunction (ED) is a common condition that may be associated with cardiovascular disease.
- Fragmented QRS (fQRS) on an electrocardiogram can indicate underlying cardiac abnormalities.
- Left ventricular (LV) systolic function is a key indicator of heart health.
Purpose of the Study:
- To investigate the association between fragmented QRS (fQRS) and left ventricular (LV) systolic function in patients with erectile dysfunction (ED).
- To determine if fQRS is a marker for subclinical LV dysfunction in ED patients without known coronary artery disease (CAD).
Main Methods:
- Compared 106 ED patients (without CAD) to 54 healthy controls.
- Assessed LV systolic function using speckle tracking echocardiography, measuring global longitudinal strain (GLS) and global circumferential strain (GCS).
- Subdivided ED patients into fQRS-positive (fQRS+) and fQRS-negative (fQRS-) groups for comparison.
Main Results:
- fQRS was significantly more frequent in ED patients (p = 0.01), especially in severe ED (p < 0.001).
- fQRS+ patients exhibited significantly lower LV-GLS (17.46 ± 1.37%) and LV-GCS (17.33 ± 0.81%) compared to fQRS- patients (p ≤ 0.001).
- fQRS and age were independent predictors of reduced LV-GLS.
Conclusions:
- Fragmented QRS (fQRS) is more prevalent in patients with erectile dysfunction (ED), even without overt coronary artery disease (CAD).
- The presence of fQRS in ED patients is linked to significantly impaired LV systolic function (lower GLS and GCS).
- fQRS may serve as a marker for subclinical left ventricular dysfunction in individuals with ED.
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