Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electrical Current01:10

Electrical Current

7.2K
Electrical current is defined as the rate at which charge flows. When there is a large current present, such as that used to run a refrigerator, a large amount of charge moves through the wire in a small amount of time. If the current is small, such as that used to operate a handheld calculator, a small amount of charge moves through the circuit over a long period of time. The SI unit for current is the ampere (A), named for the French physicist André-Marie Ampère (1775–1836).
7.2K
Gravitational Potential Energy for Extended Objects01:07

Gravitational Potential Energy for Extended Objects

2.0K
Consider a system comprising several point masses. The coordinates of the center of mass for this system can be expressed as the summation of the product of each mass and its position vector divided by the total mass:
2.0K
Role of Septins01:02

Role of Septins

2.2K
Septins are the recently discovered fourth major protein component of the cytoskeleton, along with microfilaments, microtubules, and intermediate filaments. These proteins can associate with other cytoskeletal filaments and carry out varied roles or can be free-floating in the cytoplasm.
Cellular Functions of Septins
Recent studies have revealed the multifaceted roles of septins in various cellular processes such as cytokinesis, ciliogenesis, and neurogenesis. Septins act as scaffolds and...
2.2K
The Role of Culture01:23

The Role of Culture

419
Culture plays a crucial role in shaping self-identity and influencing thought and behavior, a foundational interest within social psychology. The multicultural perspective recognizes that individuals do not exist in a vacuum; instead, their experiences, perceptions, and actions are deeply influenced by the intersecting dimensions of their cultural, ethnic, and social group affiliations.Cultural Influence on Self-Identity and Social PerceptionCultural frameworks inform how individuals define...
419
Current Density01:21

Current Density

5.1K
The total amount of current flowing through one unit value of a cross-sectional area is referred to as current density. If the current flow is uniform, the amount of current flowing through a conductor is the same at all points along the conductor, even if the conductor area varies. The current density consists of the local magnitude and direction of the charge flow, which varies from point to point. Current density is measured in amperes per meter square, and direction is defined as the net...
5.1K
Eddy Currents01:25

Eddy Currents

2.6K
Since eddy currents occur only in conductors, magnets can separate metals from other materials. For example, in a recycling center, trash is dumped in batches down a ramp, beneath which lies a powerful magnet. Conductors in the trash are slowed by eddy currents, while nonmetals in the trash move on, separating from the metals. This works for all metals, not just ferromagnetic ones.
Other major applications of eddy currents appear in metal detectors and the braking systems of trains and roller...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Protocol for Mesothelioma Observational study of Risk prediction and Generation of paired benign-meso tissue samples, Including a Nested MRI Substudy (Meso-ORIGINS).

BMJ open respiratory research·2026
Same author

Identifying Two New Ros/MucR Proteins: An Atypical Structure with a Divergent Function.

Biomolecules·2026
Same author

Establishing the top 10 research priorities for lung volume reduction treatment for people with COPD.

Thorax·2026
Same author

Impact of a national mesothelioma network on outcomes including survival.

Thorax·2026
Same author

Sporozoite egress from Plasmodium oocysts requires a trimeric NF-Y-like complex.

Communications biology·2026
Same author

A Multifactorial Model to Predict the Surgical Complexity of Lung Resection After Neoadjuvant Chemoimmunotherapy.

Annals of thoracic surgery short reports·2026

Related Experiment Video

Updated: Feb 2, 2026

Author Spotlight: Evaluating Therapeutic Strategies to Enhance Liver Regeneration
05:25

Author Spotlight: Evaluating Therapeutic Strategies to Enhance Liver Regeneration

Published on: May 24, 2024

3.6K

Extended pleurectomy decortication: the current role.

Rocco Bilancia1, Marco Nardini2, David A Waller3

  • 1Department of Thoracic Surgery, Golden Jubilee National Hospital, Glasgow, UK.

Translational Lung Cancer Research
|November 20, 2018
PubMed
Summary
This summary is machine-generated.

Extended pleurectomy/decortication (EPD) is a viable alternative to extrapleural pneumonectomy for mesothelioma surgery. However, its use requires careful patient selection due to varying evidence and ongoing trials comparing it to less invasive options.

Keywords:
Pleural mesotheliomapleurectomy/decortication (P/D)surgery

More Related Videos

Quaternary Structure Modeling Through Chemical Cross-Linking Mass Spectrometry: Extending TX-MS Jupyter Reports
05:18

Quaternary Structure Modeling Through Chemical Cross-Linking Mass Spectrometry: Extending TX-MS Jupyter Reports

Published on: October 20, 2021

2.7K
The Combination of Transcranial Alternating Current Stimulation and Electroencephalogram
06:14

The Combination of Transcranial Alternating Current Stimulation and Electroencephalogram

Published on: October 10, 2025

523

Related Experiment Videos

Last Updated: Feb 2, 2026

Author Spotlight: Evaluating Therapeutic Strategies to Enhance Liver Regeneration
05:25

Author Spotlight: Evaluating Therapeutic Strategies to Enhance Liver Regeneration

Published on: May 24, 2024

3.6K
Quaternary Structure Modeling Through Chemical Cross-Linking Mass Spectrometry: Extending TX-MS Jupyter Reports
05:18

Quaternary Structure Modeling Through Chemical Cross-Linking Mass Spectrometry: Extending TX-MS Jupyter Reports

Published on: October 20, 2021

2.7K
The Combination of Transcranial Alternating Current Stimulation and Electroencephalogram
06:14

The Combination of Transcranial Alternating Current Stimulation and Electroencephalogram

Published on: October 10, 2025

523

Area of Science:

  • Thoracic surgery
  • Surgical oncology
  • Malignant pleural mesothelioma treatment

Background:

  • Extended pleurectomy/decortication (EPD) is a complex surgical procedure for malignant pleural mesothelioma.
  • Technical aspects of EPD are debated among specialists due to its rarity and concentration in specialized centers.
  • EPD is increasingly accepted as an alternative to extrapleural pneumonectomy, preserving lung function.

Purpose of the Study:

  • To discuss the indications and considerations for extended pleurectomy/decortication in mesothelioma surgery.
  • To evaluate the role of EPD in comparison to less radical and non-surgical treatments.
  • To highlight the ongoing research and clinical dilemmas surrounding EPD.

Main Methods:

  • Review of current surgical practices and literature regarding extended pleurectomy/decortication.
  • Discussion of comparative effectiveness with extrapleural pneumonectomy and video-assisted partial pleurectomy.
  • Consideration of evidence from randomized controlled trials, including MARS2.

Main Results:

  • Extended pleurectomy/decortication is a favorable alternative to extrapleural pneumonectomy for selected patients.
  • Video-assisted partial pleurectomy may be preferable for patients with poorer prognostic factors, though evidence shows no survival benefit over talc pleurodesis.
  • The definitive role of EPD is pending results from ongoing trials comparing surgical and non-surgical management.

Conclusions:

  • Extended pleurectomy/decortication offers a lung-sparing approach for mesothelioma but requires careful patient selection.
  • Clinical decisions regarding EPD are complicated by limited high-grade evidence and the need for further research.
  • The future utility of EPD may be influenced by its comparison with non-surgical treatments in upcoming studies.