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Data on microcirculatory perfusion dips in the resting nail bed
Robin Mirdell1,2, Aukje Nienke Lemstra-Idsardi3, Simon Farnebo1,2
1Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Data in Brief
|November 21, 2018
Summary
This study reveals irregular microcirculation variations, termed "perfusion dips," in the resting nail bed. These dips were abolished by a digital nerve block, indicating their neural origin.
Area of Science:
- Physiology
- Microcirculation research
- Biomedical engineering
Background:
- The microcirculation plays a crucial role in tissue oxygenation and nutrient delivery.
- Understanding spontaneous variations in microvascular blood flow is essential for diagnosing circulatory disorders.
- Previous research has not fully characterized the dynamics of perfusion in the resting nail bed.
Purpose of the Study:
- To present raw data on spontaneous perfusion variations in the human nail bed.
- To investigate the nature and potential causes of observed "perfusion dips."
- To provide an algorithm for quantifying these perfusion dips.
Main Methods:
- Laser speckle contrast imaging (LSCI) was employed to record microcirculation perfusion.
- Data were collected from 10 healthy subjects performing 21 recordings.
- Recordings included varying acclimatization times and a digital nerve block intervention.
Main Results:
- The study identified highly irregular perfusion variations, termed "perfusion dips," in the resting nail bed.
- These perfusion dips were significantly reduced or abolished following a digital nerve block.
- An algorithm for quantifying perfusion dips was developed and is included with the data.
Conclusions:
- Spontaneous "perfusion dips" occur in the microcirculation of the resting nail bed.
- These dips appear to be modulated by neural activity, as evidenced by their abolition via nerve block.
- The provided data and algorithm facilitate further research into nail bed microcirculation and its regulation.
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