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Imaging Studies I: CT and MRI

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Robotically assisted long bone biopsy under MRI: cadaver study results.

Sunghwan Lim1, Karun Sharma2, Pan Li1

  • 1Robotics Laboratory, Brady Urological Institute, Johns Hopkins University, Baltimore, MD, USA.

International Journal of Computer Assisted Radiology and Surgery
|November 21, 2018
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Summary
This summary is machine-generated.

This study demonstrates a novel MR-safe robotic system for precise bone biopsies in pediatric patients, aiming to reduce radiation exposure. The robot achieved high accuracy, showing feasibility for MRI-guided procedures.

Keywords:
CadaverLong bone biopsyMR-safeMRIRobot

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Area of Science:

  • Medical Robotics
  • Interventional Radiology
  • Pediatric Oncology

Background:

  • Bone biopsies are crucial for diagnosing pediatric bone cancers and infections.
  • Current procedures often involve radiation exposure.
  • There is a need for advanced imaging guidance and robotic assistance.

Purpose of the Study:

  • To design and construct an MR-safe robot for bone biopsies.
  • To evaluate the feasibility of using this robot for femur and tibia biopsies in a cadaver model under MRI guidance.
  • To pave the way for reduced radiation exposure in pediatric bone biopsy procedures.

Main Methods:

  • An entirely nonmetallic, MR-safe robot with pneumatic actuators and optical encoders was developed.
  • The robot was mounted on an MRI table for biopsy procedures on a cadaver leg.
  • Ten bone biopsy targets (five femur, five tibia) were sampled using MRI guidance and a battery-powered drill.
  • CT scans were used post-procedure to verify biopsy site accuracy.

Main Results:

  • The MR-safe robotic system achieved an average targeting accuracy of 1.43 mm.
  • The robot demonstrated MRI transparency without degrading image quality.
  • Workflow analysis indicated an average setup time of 41 minutes for the first biopsy and 22 minutes for subsequent biopsies.

Conclusions:

  • The study confirms the feasibility of an MR-safe robotic system for precise, MRI-guided bone biopsies.
  • This technology has the potential to improve diagnostic accuracy and reduce radiation exposure in children.
  • Future research will focus on developing an MR-safe drill and progressing towards clinical trials in pediatric patients.