Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Sep 12, 2025

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
05:35

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

442

ProBot: Robot-Ultrasound Probe for Transrectal and Transperineal Prostate Biopsy.

Dan Stoianovici, Sunghwan Lim, Kunio Hashiba

    IEEE Transactions on Bio-Medical Engineering
    |August 8, 2025
    PubMed
    Summary

    A novel robotic prostate biopsy device, ProBot, offers precise, skill-independent targeting. This innovation aims to improve prostate cancer (PCa) management by reducing variability in biopsy outcomes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Case of Basal Cell Prostate Cancer and Recurrence With Prostatic Adenocarcinoma in a United States Military Veteran Exposed to Agent Orange.

    Clinical case reports·2026
    Same author

    Urologist and radiologist contributions to variation in prostate cancer detection at fusion biopsy.

    BJU international·2026
    Same author

    External Validation of the PRI-MUS Scoring System: A Secondary Analysis of the OPTIMUM Randomized Controlled Trial.

    The Journal of urology·2026
    Same author

    A microfluidic platform for multi-marker profiling of extracellular vesicles from single-cell-derived clones.

    bioRxiv : the preprint server for biology·2026
    Same author

    Using sunrise to surmise acute transient patellar dislocation.

    Emergency radiology·2026
    Same author

    Prostate cancer molecular subtypes in systematic versus MRI-targeted biopsy cores at active surveillance: association of PTEN and ERG status with extreme grade reclassification.

    Histopathology·2025

    Area of Science:

    • Urology
    • Robotics
    • Medical Imaging

    Background:

    • Prostate cancer (PCa) incidence is rising, necessitating improved diagnostic tools.
    • Current MRI-ultrasound fusion biopsy methods often rely on retrofitted ultrasound probes, leading to potential prostate deformation and fusion errors.
    • Robotic assistance in biopsy procedures can potentially decrease the skill dependency and variability among urologists.

    Purpose of the Study:

    • To develop and present a novel, cohesive ultrasound-robotic probe (ProBot) for prostate biopsy.
    • To enable a unique needle insertion path and minimize prostate deformation during MRI-guided biopsy.
    • To assess the feasibility and precision of the ProBot system in pre-clinical and initial clinical settings.

    Main Methods:

    • Designed ProBot with a side-fire probe and a two-degrees-of-freedom robotic rotation to minimize gland manipulation.

    More Related Videos

    Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
    09:11

    Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

    Published on: April 9, 2019

    21.7K
    A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
    06:08

    A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

    Published on: March 21, 2025

    376

    Related Experiment Videos

    Last Updated: Sep 12, 2025

    Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
    05:35

    Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

    Published on: June 6, 2025

    442
    Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
    09:11

    Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

    Published on: April 9, 2019

    21.7K
    A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
    06:08

    A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

    Published on: March 21, 2025

    376
  • Integrated a robotic angulation mechanism for needle targeting, allowing access to any gland location.
  • Developed a specialized probe and Remote Center-of-Motion (RCM) robot kinematics, along with transrectal and transperineal adapters.

    • Main Results:

    • Pre-clinical evaluations demonstrated sub-millimeter targeting accuracy.
    • The sterilization process for the ProBot device was successfully validated.
    • Initial clinical application involved successful transrectal prostate biopsies in two patients under IRB approval.

    Conclusions:

    • ProBot is a novel, compact, and precise robotic device for prostate biopsy, showing successful pilot clinical evaluation.
    • The system's design minimizes prostate deformation, addressing a key challenge in current fusion biopsy techniques.
    • This precision, skill-independent biopsy device holds potential to significantly impact prostate cancer management, warranting further clinical trials.