Related Experiment Video
Updated: Feb 2, 2026
07:20
Stimulation Location Determination using a 3D Digitizer with High-Definition Transcranial Direct Current Stimulation
Published on: December 20, 2019
7.4K
Manipulation of Human Verticality Using High-Definition Transcranial Direct Current Stimulation
Taiza E G Santos1, Diandra B Favoretto1, Iman Ghodratti Toostani2,3
1Department of Neuroscience and Behavioral Sciences, Ribeirao Preto Medical School University of Sao Paulo, Ribeirão Preto, Brazil.
Frontiers in Neurology
|November 22, 2018
Summary
High-definition transcranial direct current stimulation (HD-tDCS) over the temporo-parietal junction modulates visual and postural control. This study establishes dose-response effects for potential clinical applications.
Area of Science:
- Neuroscience
- Neuromodulation
- Clinical Trials
Background:
- Conventional transcranial direct current stimulation (tDCS) can alter subjective visual vertical (SVV) and postural control.
- High-definition tDCS (HD-tDCS) offers improved cortical stimulation focality compared to conventional tDCS.
- Establishing dose-response effects for HD-tDCS is crucial for clinical relevance.
Purpose of the Study:
- Investigate polarity and intensity-dependent effects of HD-tDCS on the right temporo-parietal junction (TPJ).
- Assess behavioral (SVV, weight-bearing asymmetry) and physiological (EEG-PSD) outcomes.
- Determine the feasibility, safety, and tolerability of the HD-tDCS protocol.
Main Methods:
- Three randomized, double-blind, crossover phase I clinical trials in healthy adults.
- HD-tDCS3x1 montage over the right TPJ.
- Tested 1, 2, and 3 mA intensities with anode center, cathode center, or sham stimulation.
Main Results:
- Significant SVV deviation observed with cathode center stimulation, increasing with intensity.
- Significant weight-bearing asymmetry (WBA) dependent on stimulation polarity.
- Increased gamma band EEG power spectral density (PSD) at 3 mA under cathode stimulation.
Conclusions:
- Converging evidence supports focal neuromodulation via HD-tDCS over the right TPJ.
- Modulation of physiology and behavior has potential clinical applications.
- The tested HD-tDCS protocol is feasible, safe, and tolerable.
Keywords:
electroencephalographyhigh-definition transcranial direct current stimulationpostural controltemporo-parietal junctionverticalityMore Related Videos
15:05Technique and Considerations in the Use of 4x1 Ring High-definition Transcranial Direct Current Stimulation HD-tDCS
Published on: July 14, 2013
38.5K
06:11High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity
Published on: September 26, 2025
960
Related Concept Videos
01:29Definite Integral
71
Consider a real-valued function defined on a closed interval. One of the fundamental objectives in calculus is to determine the area under the graph of such a function. When an exact computation is not readily available, this area can be estimated by dividing the interval into a finite number of equal subintervals. Each subinterval corresponds to a rectangle whose width is the length of the subinterval and whose height is determined by the value of the function at a selected point within that...
71
01:23Vertical Curve: Problem Solving
493
Vertical curves provide the transition between two roadway grades, ensuring safety, comfort, and functionality. Calculating elevations at specific stations along the curve involves several systematic steps based on the curve's geometry and provided design parameters.The vertical curve is defined by its length, grades, Point of Vertical Intersection (P.V.I.) location, and P.V.I. elevation. The stations of the Point of Vertical Curvature (P.V.C.), where the curve begins, and the Point of Vertical...
493
01:26Definition of z-Transform
1.6K
The z-transform is a powerful mathematical tool used in the analysis of discrete-time signals and systems. It is an essential analytical tool, analogous to the Laplace transform used in continuous-time systems. It plays a crucial role in the analysis of signals and systems, complementing the discrete-time Fourier transform. Both the z-transform and the Laplace transform convert differential or difference equations into algebraic equations, simplifying the process of solving complex problems.
1.6K
01:24Introduction to Vertical Curves
594
Vertical curves are parabolic transitions that connect different grades on highways and railroads, ensuring a smooth alignment between back and forward tangents. The back tangent represents the initial grade, while the forward tangent defines the subsequent grade. These curves can be symmetrical, with equal tangent lengths, or nonsymmetrical, with varying lengths. The key points defining a vertical curve include the Point of Vertical Intersection (P.V.I.), where the tangents meet; the Point of...
594
01:30Properties of Definite Integral I
61
A car’s motion over time can be effectively analyzed using integral calculus, particularly through the concept of the definite integral applied to a velocity–time relationship. The definite integral describes how velocity accumulates over a specified time interval to produce total displacement. From a geometric perspective, this displacement is interpreted as the area under the velocity–time curve. Several key properties of definite integrals make it easier to analyze motion...
61
01:27The Precise Definition of a Limit
304
Understanding the formal definition of a limit is essential for precise mathematical analysis. This concept allows us to rigorously determine how a function behaves near a particular point without relying on ambiguous notions such as "getting close." The ε-δ definition plays a foundational role in calculus, ensuring analytical clarity and logical consistency in limit evaluation.The formal definition states that the limit of a function f(x) as x approaches a is L, written asif for...
304