Multiple oral ulcers caused by incorrect use of oral bisphosphonate in a patient with dementia: A case report
Related Experiment Video
Updated: Feb 2, 2026

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
Published on: March 1, 2024
Takanori Eguchi1, Akihiko Basugi1, Ikuyo Kanai1
1Department of Oral and Maxillofacial Surgery, Toshiba Rinkan Hospital, Sagamihara, Japan.
Abstract:
It is not widely known that incorrect use of oral bisphosphonates (BPs), such as chewing the medication, can cause oral ulcers. An 83-year-old woman with dementia was referred to our clinic with multiple oral ulcers. Blood and histopathological examinations were inconclusive. Further questioning revealed that the patient chewed the oral BP, resulting in oral ulceration. Patients with loss of cognitive function, such as dementia, are at risk of oral ulcers caused by incorrect use of BPs.
Related Concept Videos
Dosage Regimen: Multiple Oral Dosage
Oral Cavity
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Oral Hypoglycemic Agents: Glinides
Psychosexual Stages of Personality: Oral
Weaning, typically occurring...
Data Reporting and Recording
Assessing Body Temperature - Oral
Step 1:
Start by practicing proper hand hygiene to prevent the spread of microorganisms.
Step 2:
Take the thermometer out of the charging unit, switch it on, and wait for the ready sign.
Step 3:
Gently slide the probe cover until a click is heard. This simple action prevents cross-contamination and ensures the correct placement of the probe cover.
Step 4:
Instruct the patient to open their mouth and place...

