Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Beats

Beats

The study of music provides many examples of the superposition of waves and the constructive and destructive interference that occurs. Very few examples of music being performed consist of a single source playing a single frequency for an extended period of time. A single frequency of sound for an extended period might be monotonous to the point of irritation, similar to the unwanted drone of an aircraft engine or a loud fan. Music is pleasant and exciting due to mixing the changing frequencies...

The Evidence for Evolution

The Evidence for Evolution

Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.

Convergent Evolution

Convergent Evolution

Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.

Predicting Molecular Geometry

Predicting Molecular Geometry

VSEPR Theory for Determination of Electron Pair Geometries

Eukaryotic Evolution

Eukaryotic Evolution

The endosymbiont theory is the most widely accepted theory of eukaryotic evolution; however, its progression is still somewhat debated. According to the nucleus-first hypothesis, the ancestral prokaryote first evolved a membrane to enclose DNA and form the nucleus. Conversely, the mitochondria-first hypothesis suggests that the nucleus was formed after endosymbiosis of mitochondria.
Contrary to the endosymbiont theory, the eukaryote-first hypothesis proposes that the simpler prokaryotic and...

Synteny and Evolution

Synteny and Evolution

John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Engineering non-ribosomal peptide synthesis: tuning the antibiotics engine of the microbial world.

Critical reviews in biotechnology·2026

Same author

Slowpoke: An Automated Golden Gate Cloning Workflow for Opentrons OT-2 and Flex.

ACS synthetic biology·2026

Same author

Programmable cell-cell adhesion in synthetic yeast communities for improved bioproduction.

Nature chemical biology·2026

Same author

Bacterially grown living materials with resistant and on-demand functionality.

Science advances·2025

Same author

YTK Display-and-Secrete: Screening for Optimal Protein Secretion Elements in <i>Saccharomyces cerevisiae</i>.

ACS synthetic biology·2025

Same author

Iterative SCRaMbLE for engineering synthetic genome modules and chromosomes.

Nature communications·2025

Same journal

Mind the Porins: Differential Effects of Porin Knockouts and Overexpression on Glucose and Xylose Uptake and Utilization in Pseudomonas putida.

Microbial biotechnology·2026

Same journal

Coumarins Disrupt Cell-Cell Communication and Virulence in Priority Pathogens: Targeting the PQS Signalling System in Pseudomonas aeruginosa.

Microbial biotechnology·2026

Same journal

Engineering Pseudomonas protegens as a Targeted Antifungal-Effector Delivery Chassis via Heterologous Type III Secretion System Reconstitution.

Microbial biotechnology·2026

Same journal

Adaptive Laboratory Evolution Unlocks Membrane Permeability as a Key Limitation in Long-Chain Alcohol Metabolism by Pseudomonas putida KT2440.

Microbial biotechnology·2026

Same journal

Correction to 'Unveiling the Potential of Lentilactobacillus hilgardii in Malolactic Fermentation: Comparative Genomics and Fermentation Dynamics'.

Microbial biotechnology·2026

Same journal

NADPH Dehydrogenase Gene Regulates Energy Distribution and Fatty Acid Metabolism During Fruiting Body Formation in the Filamentous Fungus Podospora anserina.

Microbial biotechnology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 2, 2026

Visualizing the Beating Heart in Drosophila

Visualizing the Beating Heart in Drosophila

Published on: September 28, 2009

Predicting how evolution will beat us.

¹Department of Bioengineering, Imperial College London, London, SW7 2AZ, UK.

Microbial Biotechnology

|November 22, 2018

Summary

This summary is machine-generated.

This Crystal Ball article explores future models and tools for predicting mutations that inactivate engineered plasmids. Such advancements aim to improve genetic engineering and synthetic biology applications.

More Related Videos

Molecular Evolution of the Tre Recombinase

Molecular Evolution of the Tre Recombinase

Published on: May 29, 2008

Author Spotlight: Advancing Protein Engineering – Harnessing Evolution Through PRANCE and Lab Automation

Author Spotlight: Advancing Protein Engineering – Harnessing Evolution Through PRANCE and Lab Automation

Published on: January 12, 2024

Related Experiment Videos

Last Updated: Feb 2, 2026

Visualizing the Beating Heart in Drosophila

Visualizing the Beating Heart in Drosophila

Published on: September 28, 2009

Molecular Evolution of the Tre Recombinase

Molecular Evolution of the Tre Recombinase

Published on: May 29, 2008

Author Spotlight: Advancing Protein Engineering – Harnessing Evolution Through PRANCE and Lab Automation

Author Spotlight: Advancing Protein Engineering – Harnessing Evolution Through PRANCE and Lab Automation

Published on: January 12, 2024

Area of Science:

Synthetic biology
Molecular biology
Bioinformatics

Background:

Engineered plasmids are crucial tools in biotechnology and research.
Unpredictable mutations can inactivate plasmids, hindering their function.
Predictive models are needed to ensure plasmid stability and efficacy.

Purpose of the Study:

To forecast the development of predictive models and tools.
To anticipate the capability of identifying inactivating mutations in engineered plasmids.
To discuss the potential impact on synthetic biology and genetic engineering.

Main Methods:

Conceptual exploration of future predictive modeling techniques.
Review of current understanding of plasmid mutation dynamics.
Discussion of potential computational and experimental approaches.

Main Results:

The article posits the future development of sophisticated predictive models.
It highlights the potential for tools to identify specific mutation accumulation patterns.
Anticipates enhanced control over engineered genetic elements.

Conclusions:

Predictive models for plasmid mutation are a foreseeable advancement.
These tools could significantly enhance the reliability of engineered plasmids.
Future research should focus on developing and validating such predictive capabilities.