Related Experiment Video
Updated: Feb 2, 2026
04:51
Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
10.4K
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange During Electroconvulsive Therapy: A Feasibility Study
Yori Jonker, Dennis J Rutten1, Eric R van Exel2
1Medical Faculty, VU University.
The Journal of ECT
|November 22, 2018
Summary
Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) safely oxygenated patients during electroconvulsive therapy (ECT). This novel method proved comfortable and effective, offering a viable alternative to standard face mask ventilation during ECT procedures.
Area of Science:
- Anesthesiology
- Critical Care Medicine
- Neurology
Background:
- Electroconvulsive therapy (ECT) requires general anesthesia and airway management.
- Standard face mask ventilation is challenging during ECT-induced seizures.
- Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) offers potential for improved oxygenation during apnea.
Purpose of the Study:
- To evaluate the feasibility and safety of THRIVE for oxygenation during ECT.
- To assess patient comfort with THRIVE compared to traditional face mask ventilation.
- To determine THRIVE's impact on apnea tolerance and oxygenation during ECT.
Main Methods:
- A single-center feasibility study involving 13 patients with treatment-resistant depression undergoing ECT.
- THRIVE was used for airway management during 20 ECT sessions.
- Patient comfort was assessed via survey, comparing THRIVE to prior face mask experiences.
Main Results:
- No instances of desaturation occurred during THRIVE use.
- Patient comfort levels were comparable between THRIVE and face mask ventilation.
- THRIVE did not appear to shorten seizure duration compared to previous face mask ventilation.
Conclusions:
- THRIVE is a safe and novel method for oxygenation during electroconvulsive therapy.
- THRIVE demonstrates feasibility as an alternative airway management technique in ECT.
- Further research may explore THRIVE's broader applications in procedures requiring apnea oxygenation.
More Related Videos
Related Concept Videos
01:30Electroconvulsive Therapy
1.1K
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
1.1K
01:14Ventilatory Modes
1.5K
Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
1.5K
02:06Social Exchange Theory
40.8K
We have discussed why we form relationships, what attracts us to others, and different types of love. But what determines whether we are satisfied with and stay in a relationship? One theory that provides an explanation is social exchange theory. According to social exchange theory, we act as naïve economists in keeping a tally of the ratio of costs and benefits of forming and maintaining a relationship with others (Rusbult & Van Lange, 2003).
40.8K
01:26Social Exchange Theory
458
As formulated by John Thibaut and Harold Kelley, Social Exchange Theory explains human relationships as economic-like exchanges that maximize rewards and minimize costs. This theory suggests that individuals engage in relationships to gain benefits and reduce burdens, similar to economic transactions. It has been widely applied to various types of relationships, including romantic, professional, and social interactions.Rewards and Costs in RelationshipsRelationship rewards include emotional...
458
01:20Gas Exchange and Transport
76.9K
Gas exchange, the intake of molecular oxygen (O2) from the environment and the outflow of carbon dioxide (CO2) into the environment, is necessary for cellular function. Gas exchange during respiration occurs largely via the movement of gas molecules along pressure gradients. Gas travels from areas of higher partial pressure to areas of lower partial pressure. In mammals, gas exchange occurs in the alveoli of the lungs, which are adjacent to capillaries and share a membrane with them.
76.9K
01:28Capillary Exchange
11.2K
The cardiovascular system's chief role is to disseminate gases, nutrients, waste, and other substances to the body's cells. Small molecules like gases, lipids, and lipid-soluble substances directly diffuse through capillary wall endothelial cell membranes. Glucose, amino acids, and ions, including sodium, potassium, calcium, and chloride, use transporters for facilitated diffusion via membrane-specific channels. Glucose, ions, and bigger molecules may also pass through intercellular...
11.2K