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Dystrophic calcinosis in a patient with overlap syndrome (scleroderma and rheumatoid arthritis) treated by
Sang Yeob Lee1, Sung Won Lee, Won Tae Chung
1Department of Rheumatology, Division of Internal Medicine, Medical College of Dong-A University, Pusan, Republic of Korea.
Rationale:
Dystrophic calcinosis occurs in chronically damaged tissue in patients with complicated autoimmune diseases. The therapeutic options are limited, and the treatment response rate is variable. Here, we describe a rare case of dystrophic calcinosis treated with leflunomide in a patient with overlap syndrome.
Patient Concerns:
A 53-year-old woman who was diagnosed with overlaps syndrome (systemic sclerosis [SSc] with rheumatoid arthritis [RA]), presented to our hospital with pain and swelling in both wrists, and underwent radiography, bone scan, and biopsy examination.
Diagnoses:
This patient was diagnosed with dystrophic calcinosis in overlaps syndrome.
Interventions:
The conventional disease-modifying drugs were not effective. Hence, leflunomide was administered.
Outcomes:
Simple radiography and bone scan showed resolved mass-like dystrophic calcinosis on both wrists of the patient after the use of leflunomide.
Lessons:
The control of underlying disease is important in the treatment of dystrophic calcinosis. The use of leflunomide maybe an option in treatment of dystrophic calcinosis combined with RA.
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