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Buprenorphine-Sustained Release Alters Hemodynamic Parameters in a Rat Burn Model

Ashley N Guillory1, Robert P Clayton2, Anesh Prasai3

  • 1Shriners Hospitals for Children(®)-Galveston, Galveston, Texas; Department of Surgery, University of Texas Medical Branch, Galveston, Texas; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, Texas.

The Journal of Surgical Research
|November 23, 2018
PubMed
Summary

Buprenorphine-SR significantly altered hemodynamic responses in a rat burn model, affecting blood pressure and heart rate. This suggests caution when using buprenorphine-SR in severe burn injury research.

Keywords:
AnalgesiaBlood pressureCytokinesHeart ratePain management

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