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Cutaneous plasmacytic infiltrates.

S M Torres1, J L Sánchez

  • 1Department of Dermatology, University of Puerto Rico, School of Medicine, San Juan.

The American Journal of Dermatopathology
|August 1, 1988
PubMed
Summary
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This review examines skin disorders characterized by plasma cells in tissue biopsies. Understanding plasma cell presence aids in diagnosing, predicting outcomes, and understanding the causes of these diverse skin conditions.

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Plasma cells are key immune cells involved in antibody production.
  • Certain skin conditions exhibit a characteristic infiltrate of plasma cells in histopathology.
  • Understanding the role of plasma cells is crucial for diagnosing and managing various dermatoses.

Purpose of the Study:

  • To review skin disorders featuring plasma cell infiltrates.
  • To highlight the diagnostic, prognostic, and pathogenetic significance of plasma cells in these conditions.

Main Methods:

  • Literature review of skin disorders with plasma cell infiltrates.
  • Histopathologic examination findings are correlated with clinical diagnoses.

Main Results:

  • Identified a spectrum of skin disorders including inflammatory, neoplastic, and miscellaneous conditions with plasma cell infiltrates.

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  • Demonstrated the correlation between plasma cell presence and disease characteristics.

    • Conclusions:

    • Histopathologic identification of plasma cells is a significant finding in various skin disorders.
    • Plasma cell infiltrates are relevant to the diagnosis, prognosis, and pathogenesis of these dermatologic conditions.