Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Decision Making01:20

Decision Making

970
Decision-making is a fundamental cognitive process that involves evaluating alternatives and selecting among them. This process can range from simple choices, such as deciding what to wear, to complex decisions, like choosing a major in college or a career path. The complexity of the decision often dictates the approach we use, which can be broadly categorized into two types: automatic and controlled decision-making.
Automatic decision-making is fast, intuitive, and relies on gut feelings...
970
Decision Making: P-value Method01:09

Decision Making: P-value Method

6.9K
The process of hypothesis testing based on the P-value method includes calculating the P- value using the sample data and interpreting it.
First, a specific claim about the population parameter is proposed. The claim is based on the research question and is stated in a simple form. Further, an opposing statement to the claim  is also stated. These statements can act as null and alternative hypotheses:  a null hypothesis would be a neutral statement while the alternative hypothesis can...
6.9K
Association Areas of the Cortex01:21

Association Areas of the Cortex

9.4K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
9.4K
Decision Making: Traditional Method01:14

Decision Making: Traditional Method

5.4K
The process of hypothesis testing based on the traditional method includes calculating the critical value, testing the value of the test statistic using the sample data, and interpreting these values.
First, a specific claim about the population parameter is decided based on the research question and is stated in a simple form. Further, an opposing statement to this claim is also stated. These statements can act as null and alternative hypotheses, out of which a null hypothesis would be a...
5.4K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

7.5K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
7.5K
Somatosensory, Motor, and Association Cortex01:23

Somatosensory, Motor, and Association Cortex

2.7K
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neuropixels Opto: combining high-resolution electrophysiology and optogenetics.

Nature methods·2026
Same author

Dorsal prefrontal cortex drives perseverative behavior in mice.

Nature communications·2026
Same author

Brainwide blood volume reflects opposing neural populations.

Nature·2026
Same author

Glutamate indicators with increased sensitivity and tailored deactivation rates.

Nature methods·2025
Same author

Brain-wide representations of prior information in mouse decision-making.

Nature·2025
Same author

Mapping the visual cortex with Zebra noise and wavelets.

bioRxiv : the preprint server for biology·2025
Same journal

The exquisite mechanics of a tsetse bite.

eLife·2026
Same journal

Distinct involvements of the subthalamic nucleus subpopulations in reward-biased decision-making in monkeys.

eLife·2026
Same journal

Pink1-mediated mitophagy in the endothelium releases proteins encoded by mitochondrial DNA and activates neutrophil responses during inflammation.

eLife·2026
Same journal

Restraint of melanoma progression by cells in the local skin environment.

eLife·2026
Same journal

Brawn before bite in endemic Asian eutherian mammals after the end-Cretaceous extinction.

eLife·2026
Same journal

Experimental evolution to thermal stress indicates climate resilience in a cosmopolitan arthropod.

eLife·2026
See all related articles

Related Experiment Video

Updated: Feb 2, 2026

Integrating Visual Psychophysical Assays within a Y-Maze to Isolate the Role that Visual Features Play in Navigational Decisions
07:09

Integrating Visual Psychophysical Assays within a Y-Maze to Isolate the Role that Visual Features Play in Navigational Decisions

Published on: May 2, 2019

6.5K

Decision and navigation in mouse parietal cortex.

Michael Krumin1, Julie J Lee1, Kenneth D Harris2

  • 1UCL Institute of Ophthalmology, University College London, London, United Kingdom.

Elife
|November 24, 2018
PubMed
Summary
This summary is machine-generated.

Posterior parietal cortex (PPC) activity in mice performing virtual navigation is strongly predicted by spatial position and heading. These findings link PPC

Keywords:
cortexdecisionmousenavigationneurosciencevisual processing

More Related Videos

A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants
06:28

A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants

Published on: August 26, 2018

6.3K
Preparation of Synaptoneurosomes from Mouse Cortex using a Discontinuous Percoll-Sucrose Density Gradient
08:30

Preparation of Synaptoneurosomes from Mouse Cortex using a Discontinuous Percoll-Sucrose Density Gradient

Published on: September 17, 2011

32.8K

Related Experiment Videos

Last Updated: Feb 2, 2026

Integrating Visual Psychophysical Assays within a Y-Maze to Isolate the Role that Visual Features Play in Navigational Decisions
07:09

Integrating Visual Psychophysical Assays within a Y-Maze to Isolate the Role that Visual Features Play in Navigational Decisions

Published on: May 2, 2019

6.5K
A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants
06:28

A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants

Published on: August 26, 2018

6.3K
Preparation of Synaptoneurosomes from Mouse Cortex using a Discontinuous Percoll-Sucrose Density Gradient
08:30

Preparation of Synaptoneurosomes from Mouse Cortex using a Discontinuous Percoll-Sucrose Density Gradient

Published on: September 17, 2011

32.8K

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Computational Neuroscience

Background:

  • The posterior parietal cortex (PPC) is involved in spatial navigation, motor control, and visually guided decision-making.
  • Understanding the unified function of PPC across these domains remains a challenge.

Purpose of the Study:

  • To investigate the role of the posterior parietal cortex (PPC) in integrating spatial information and decision-making during navigation.
  • To determine how PPC neural activity encodes an animal's trajectory and choices in a virtual environment.

Main Methods:

  • Mice performed a virtual navigation task requiring visually-guided decisions.
  • Neural activity in the PPC was recorded during task performance.
  • Computational models were used to predict PPC neural activity based on spatial position, heading angle, and decision variables.

Main Results:

  • PPC neurons exhibited selectivity for specific combinations of spatial position and heading angle.
  • This neural selectivity accurately predicted individual neuron activity and collective firing patterns.
  • PPC activity primarily encoded the animal's navigation trajectory, with spatial position and heading being key predictors over decision variables.

Conclusions:

  • A significant portion of PPC activity during visually-guided navigation reflects the encoding of spatial position and heading.
  • These findings suggest that PPC plays a crucial role in representing an animal's location and orientation during navigation.
  • The study provides a unified account of PPC function, linking its roles in navigation, movement control, and decision-making.