A 40-MHz Ultrasound Transducer with an Angled Aperture for Guiding Percutaneous Revascularization of Chronic Total
Junsu Lee1, Jin Ho Chang2,3
1Department of Electronic Engineering, Sogang University, Seoul 04107, Korea. leejs@sogang.ac.kr.
Insights
A new 40-MHz forward-looking intravascular ultrasound (FL-IVUS) transducer helps surgeons visualize calcification within chronic total occlusion (CTO) lesions. This imaging advancement aims to improve guidewire crossing success rates in complex coronary artery blockages.
Area of Science:
- Cardiovascular medicine
- Medical imaging technology
- Interventional cardiology
Background:
- Chronic total occlusion (CTO) is a complete blockage of coronary arteries, often caused by atherosclerosis.
- Current angiography methods fail to image inside CTO lesions, leaving surgeons
- blind
- during guidewire crossing.
- Guidewire crossing success rates decrease significantly (from 69.0% to 32.5%) when extensive, guidewire-impermeable calcification is present.
Purpose of the Study:
- To report on a newly developed 40-MHz forward-looking intravascular ultrasound (FL-IVUS) transducer.
- To enable visualization of calcification within CTO lesions.
- To assist surgeons in making informed decisions during guidewire crossing procedures.
Main Methods:
- Development of a novel 40-MHz FL-IVUS transducer with a single element angled aperture and guidewire passage.
- Spherical deformation of the aperture to a 3 mm focal length for enhanced spatial resolution.
- Optimization of the angle between the beam direction and rotation axis to 30° for effective visualization of calcification and vessel walls.
Main Results:
- The developed FL-IVUS transducer successfully visualized calcification within CTO lesions.
- Experimental results confirmed the transducer's capability to image the blood vessel wall.
- The imaging facilitated decision-making for surgeons regarding guidewire advancement or procedural changes.
Conclusions:
- The novel FL-IVUS transducer provides crucial visualization of calcification in CTO lesions.
- This technology has the potential to improve the success rates of guidewire crossing in complex CTO interventions.
- Enhanced intra-lesional imaging empowers surgeons to navigate challenging atherosclerotic blockages more effectively.
Abstract:
Complete blockage of a coronary artery, called chronic total occlusion (CTO), frequently occurs due to atherosclerosis. To reopen the obstructed blood vessels with a stent, guidewire crossing is performed with the help of angiography that can provide the location of CTO lesions and the image of guidewire tip. Since angiography is incapable of imaging inside a CTO lesion, the surgeons are blind during guidewire crossing. For this reason, the success rate of guidewire crossing relies upon the proficiency of the surgeon, which is considerably reduced from 69.0% to 32.5% if extensive calcification, not penetrated by a guidewire, exists in CTO lesions. In this paper, a recently developed 40-MHz forward-looking intravascular ultrasound (FL⁻IVUS) transducer to visualize calcification within CTO lesions is reported. This transducer consists of a single element angled aperture and a guidewire passage. The aperture is spherically deformed to have a focal length of 3 mm in order to improve spatial resolution of FL⁻IVUS images. The angle between the beam direction and the axis of rotation is designed to be 30° to effectively visualize calcification within a CTO lesion as well as the blood vessel wall. The experimental results demonstrated that the developed FL⁻IVUS transducer facilitates visualization of calcification within CTO lesions and makes it possible to help the surgeon make decisions about whether to push the guidewire in order to cross the lesion or to change the surgical procedure.
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