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Related Concept Videos

Chirality02:25

Chirality

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Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
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Chirality in Nature02:30

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Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
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The Intermediate Value Theorem01:25

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The Intermediate Value Theorem is a foundational result in calculus that guarantees the existence of solutions within certain intervals for continuous functions. Formally, the Intermediate Value Theorem states that if a function f is continuous on the closed interval [a, b], and if N is any value between f(a) and f(b), then there exists at least one c ∈ (a, b) such that f(c) = N. This theorem is instrumental in proving the existence of roots and in analyzing the behavior of continuous...
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Intermediate filaments (IFs) do not undergo spontaneous disassembly. Enzymes, kinases, and phosphatases add and remove phosphates from specific sites to regulate their disassembly. The IF concentration in the cytoplasm also regulates the disassembly. If the concentration crosses a threshold, it activates the protein kinases in the vicinity, allowing the phosphorylation of IFs.
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Types of Intermediate Filaments01:31

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The intermediate filaments are an essential component of the cytoskeleton. Presently six types of intermediate filament have been identified. Type I and II are acidic and basic keratin proteins. Type III is of mesodermal origin and comprises four proteins: vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Vimentin is commonly found in mesenchymal cells, desmin in muscle cells, GFAP in astrocytes, while peripherin is found in peripheral nervous system neurons (PNS). Type...
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Intermediate filaments are cytoskeletal proteins with higher tensile strength and flexibility than microfilaments and microtubules. Unlike the other two cytoskeletal proteins, intermediate filament formation lacks the enzymatic activity to hydrolyze nucleotides like ATP and GTP to generate energy for polymerization. Therefore, the formation of intermediate filaments is multistep self-assembly. The involvement of any accessory proteins in intermediate filament formation has not yet been...
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Updated: Feb 2, 2026

Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles
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Intermediate States Directed Chiral Transfer on a Silver Surface.

Biao Yang1, Nan Cao1, Huanxin Ju2

  • 1Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials a Devices , Soochow University , 199 Ren'ai Road , Suzhou 215123 , P. R. China.

Journal of the American Chemical Society
|November 27, 2018
PubMed
Summary
This summary is machine-generated.

This study demonstrates a new method for 2D chiral transfer using metal-organic intermediates on a silver surface. Chirality is successfully transferred from intermediate states to final dimer products.

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Area of Science:

  • Surface chemistry
  • Chiral synthesis
  • Supramolecular chemistry

Background:

  • Chiral synthesis on surfaces is a growing field.
  • Controlling chirality in surface-assembled structures is challenging.

Purpose of the Study:

  • To develop a novel 2D chiral transfer method.
  • To investigate chiral induction via metal-organic intermediates on surfaces.

Main Methods:

  • Self-assembly of achiral molecules on Ag(100) surface.
  • Controlled annealing to form chiral metal-organic hybrids.
  • Density Functional Theory (DFT) calculations.
  • Synchrotron-based X-ray Photoelectron Spectroscopy (XPS).

Main Results:

  • Achiral 4,4'-dihydroxybiphenyl formed 2D networks.
  • Annealing induced chiral tetramer intermediates.
  • Chirality transferred from tetramers to dimer products.
  • Enantiomeric islands formed on the silver surface.

Conclusions:

  • Demonstrated a novel 2D chiral transfer mechanism.
  • Metal-organic intermediates are key to chiral induction.
  • Surface-mediated reactions can control chirality effectively.