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Published on: August 9, 2013
Reversible Acute Kidney Injury Associated with Sildenafil Overdose
Baoqiong Liu1, Lingbin Meng1, Xuan Guan1
1Internal Medicine, Florida Hospital, Orlando, USA.
Abstract:
Sildenafil is a phosphodiesterase type 5 inhibitor that is approved to treat erectile dysfunction and pulmonary hypertension. Generally, sildenafil is safe, with mild side effects. Here, we report a case of acute kidney injury caused by a sildenafil overdose. A 67-year-old man took 400 mg of sildenafil for erectile dysfunction. The patient was found to have acute kidney injury from acute tubular necrosis during hospitalization with a peak serum creatinine of 5.07 mg/dL though his renal function recovered with supportive care.
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