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Anxiety and gastrointestinal illness.

R E Clouse1

  • 1Washington University School of Medicine, St. Louis, Missouri.

The Psychiatric Clinics of North America
|June 1, 1988
PubMed
Summary

Anxiety and psychiatric disorders significantly impact gastrointestinal function, but the exact mechanisms remain unclear. Further research is needed to understand the complex emotion-gut relationship in functional bowel diseases.

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Area of Science:

  • Neurogastroenterology
  • Psychiatry
  • Gastroenterology

Background:

  • The central nervous system (CNS) significantly influences gastrointestinal (GI) functions.
  • Anxiety and psychiatric disorders are prevalent in patients with functional bowel diseases.
  • Existing knowledge of CNS control mechanisms provides a basis for understanding GI modulation by psychiatric conditions.

Purpose of the Study:

  • To explore the relationship between psychiatric disorders, particularly anxiety, and gastrointestinal dysfunction.
  • To highlight the need for further physiological studies in chronic anxiety disorders and their link to GI illness.
  • To emphasize the functional bowel diseases as a key area for investigating the biological basis of the emotion-gut axis.

Main Methods:

  • Review of existing literature on CNS control of GI functions.
  • Analysis of recent experiments on GI response to acute stress.
  • Identification of knowledge gaps in understanding chronic stress and anxiety's impact on GI health.

Main Results:

  • Central stimuli, including emotional stress, can induce measurable GI changes.
  • The precise GI responses to acute stress are not always predictable based solely on known control mechanisms.
  • There is a scarcity of detailed physiological studies on the impact of chronic anxiety disorders on GI function.

Conclusions:

  • While acute stress impacts the GI tract, these findings may not directly translate to chronic anxiety disorders.
  • Functional bowel diseases present a significant opportunity to study the biological underpinnings of the emotion-gut connection.
  • Further research is crucial to elucidate the complex interplay between psychiatric conditions and gastrointestinal health.

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