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C Velter1

  • 1Service de dermatologie, institut Gustave-Roussy, 94805 Villejuif, France.

Annales De Dermatologie Et De Venereologie
|November 28, 2018
PubMed
Summary
This summary is machine-generated.

Radiotherapy offers an effective treatment option for basal cell carcinoma, particularly for complex cases. While not a first-line therapy, it achieves high local control rates and excellent cosmetic results with manageable side effects.

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Area of Science:

  • Oncology
  • Dermatology
  • Radiation Oncology

Background:

  • Basal cell carcinoma (BCC) is frequently managed with surgical excision.
  • Radiotherapy is an alternative for inoperable or functionally/cosmetically challenging BCC cases.
  • Multidisciplinary management integrating histological assessment is crucial for BCC patients.

Purpose of the Study:

  • To review the role and efficacy of radiotherapy in managing basal cell carcinoma.
  • To evaluate treatment outcomes, including local control, cosmetic results, and side effects.

Main Methods:

  • Review of existing literature on radiotherapy for basal cell carcinoma.
  • Analysis of different radiotherapy modalities (external beam, brachytherapy) and regimens.
  • Assessment of reported local control rates, cosmetic outcomes, and adverse events.
Keywords:
Basal cellCarcinome basocellulaireCuriethérapieInterstitial brachytherapyRadiation therapyRadiothérapiecarcinoma

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Main Results:

  • Radiotherapy demonstrates high overall local control rates, ranging from 80-100%.
  • Over 90% of patients report good to excellent cosmetic outcomes following treatment.
  • Reported side effects are generally minor, though secondary malignancy risk is a consideration in young patients.

Conclusions:

  • Radiotherapy is a viable and effective treatment modality for specific basal cell carcinoma cases.
  • Further randomized studies are needed to establish optimal radiotherapy regimens.
  • Careful patient selection and consideration of potential long-term risks are essential.