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Updated: Feb 2, 2026

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
Published on: July 3, 2014
Patient Acceptance of Half-dose Vs. Half-time Molecular Breast Imaging
Tiffinee N Swanson1, Thuy D Tran1, Carrie B Hruska1
1Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Objective:
A number of strategies have been implemented at our institution to allow reductions in the administered dose or imaging time for molecular breast imaging (MBI). In this work, we examine patient opinions of whether dose reduction or time reduction is preferred.
Methods:
Sixty female volunteers were randomized to undergo MBI at either half-dose (150 MBq Tc-99m sestamibi; images acquired for 10 minutes per view) or half-time (300 MBq Tc-99m sestamibi; images acquired for 5 minutes per view). A survey was then performed to assess patient comfort and examination preferences. Survey responses were compared between groups using Fisher's exact test.
Results:
No differences were observed between groups regarding opinions of radiation dose, duration of examination, examination comfort, and willingness to undergo MBI in the future. Of those who responded, most women (39/55 [70%]) indicated a preference for the examination type they underwent, either half-dose or half-time MBI, rather than the other protocol.
Conclusions:
Survey findings support that MBI, whether performed at half-time or half-dose, is well accepted by patients.
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