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Updated: Feb 2, 2026
Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
Published on: June 7, 2019
Clinicopathologically problematic melanocytic tumors: a case-based review
Zoe Apalla1, Christina Nikolaidou1,2, Aimilios Lallas1
1First Dermatology Department, Aristotle University of Thessaloniki, Greece.
Background:
In spite of recent advances in the histopathological and molecular diagnosis of melanocytic neoplasms, a certain proportion of these lesions remain a daunting challenge for both the clinician and the pathologist.
Objectives:
To emphasize the importance of close collaboration between clinicians and pathologists in case of problematic melanocytic lesions.
Patients:
We report and discuss 5 problematic scenarios of melanocytic lesions, including tumoral melanosis, nevoid melanoma, lentiginous melanoma, spitzoid melanoma and BAPoma that may pose diagnostic difficulties in our practice.
Conclusions:
Clinico-dermoscopic-pathological correlation, with incorporation of all the available data, in problematic melanocytic skin neoplasms is of paramount importance for accurate diagnosis.
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