Related Experiment Video
Updated: Feb 2, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
Published on: July 28, 2020
Updates in adjuvant systemic therapy for melanoma
Minyoung Kwak1, Norma E Farrow2, April K S Salama3
1Department of Surgery, University of Virginia, Charlottesville, Virginia.
Abstract:
There has been a rapid increase in adjuvant therapies approved for treatment following surgical resection of stages III/IV melanoma. We review current indications for adjuvant therapy, which currently includes a heterogenous group of stages III and IV patients with melanoma. We describe several pivotal clinical trials of systemic immune therapies, targeted immune therapies, and adjuvant vaccine strategies. Finally, we discuss the evidence for selecting the most appropriate treatment regimen(s) for the individual patient.
Related Concept Videos
Gene Therapy
Second Order systems II
First Order Systems
When a first-order system is subjected to a unit-step input, its response is characterized by its transfer function. By applying the Laplace transform of the unit-step input to the transfer function, expanding the...
Second Order systems I
By reinterpreting the system, one can derive the closed-loop transfer function, which...
Group Therapy
Thermodynamic Systems
Consider an example of tea boiling in a kettle. The...

