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Updated: Feb 2, 2026

Manipulating the Murine Lacrimal Gland
Published on: November 18, 2014
A rare case of coexisting lacrimal sac adenocarcinoma and transitional cell carcinoma
Tsutomu Nomura1, Daisuke Maki, Fumihiko Matsumoto
1Department of Otolaryngology, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Kawagoe-shi, Saitama 380-8550, Japan. t-nomura@bc5.so-net.ne.jp.
Abstract:
Lacrimal sac tumors are rare and difficult to diagnose. We present a case of coexisting lacrimal sac adenocarcinoma and transitional cell carcinoma in a 73-year-old woman who presented with swelling of the inner canthus. Biopsy identified the growth as an adenocarcinoma. After dissection of the lacrimal carcinoma via a lateral rhinotomy, histopathologic examination confirmed the adenocarcinoma and identified a coexisting transitional cell carcinoma. A recurrence developed, but only of the adenocarcinoma component. For the recurrence, the patient was treated with wide resection, including the orbital contents, and subsequent irradiation. At 49 months postoperatively, the patient remained alive but with a lung metastasis. Wide resection was the key to treatment.
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