Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lattice Centering and Coordination Number02:33

Lattice Centering and Coordination Number

11.6K
The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...
11.6K
Nursing Implementation01:15

Nursing Implementation

6.2K
Implementation is the execution of the nursing care plan developed during the planning phase.
The five steps to implementing effective nursing care include reassessing the patient, reviewing and revising the existing nursing care plan, organizing the resources and care delivery, anticipating and preventing complications, and implementing nursing interventions.
6.2K
Center of Gravity00:58

Center of Gravity

6.7K
The center of gravity (COG) of an object is the point where the object's total weight is considered to be concentrated. Knowing the location of the center of gravity is useful when predicting the behavior of a moving object or designing static structures. In a uniform gravitational field, the center of gravity is similar to the center of mass (COM); yet, these two points can be positioned differently. For example, the Moon's center of mass lies very close to its geometric center, but...
6.7K
Center of Gravity01:15

Center of Gravity

2.2K
The center of gravity is the point at which an object's weight appears to be concentrated and can be used to balance the object perfectly. This point is essential in mechanics as it provides information regarding a body's stability and moments of inertia. The center of gravity does not always have to fall within the shape or boundaries of the body; it may also lie outside the body in certain cases.
To determine its location, the principle of moments can be utilized by dividing the object into...
2.2K
Center of Mass00:59

Center of Mass

2.0K
The center of mass is the point at which the total mass of an object can be said to be concentrated. It is a fundamental principle in mechanics and physics that applies to all objects regardless of their shape or size. The center of gravity is the point at which an object’s weight appears to be concentrated and can be used to balance the object perfectly.
The knowledge of the center of mass can also help us to describe and predict the motion of objects. For example, when a ball is thrown...
2.0K
What is an Experiment?01:12

What is an Experiment?

18.2K
An experiment is a planned activity carried out under controlled conditions. The purpose of an experiment is to investigate the relationship between two variables. When one variable causes change in another, we call the first variable the explanatory or independent variable. The affected variable is called the response or dependent variable. In a randomized experiment, the researcher manipulates values of the explanatory variable and measures the resulting changes in the response variable. The...
18.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum: Resistance to Immune Checkpoint Inhibitor Treatment in Non-Small Cell Lung Cancer Clinical Trials: A Perspective From Lung-MAP Investigators.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same author

Resistance to Immune Checkpoint Inhibitor Treatment in Non-Small Cell Lung Cancer Clinical Trials: A Perspective From Lung-MAP Investigators.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
Same author

Portable hepatitis C virus RNA extraction and stabilization using low-cost lab-on-a-chip style components with shelf stable reagents.

Sensors and actuators. B, Chemical·2026
Same author

Telehealth Competency Evaluation Tools: A Scoping Review.

Telemedicine journal and e-health : the official journal of the American Telemedicine Association·2026
Same author

Perpetration of intimate partner violence and suicide attempt, suicidal ideation, and non-suicidal self-harm: a cross-sectional secondary analysis using the Adult Psychiatric Morbidity Survey.

Epidemiology and psychiatric sciences·2026
Same author

Black Fathers as an Asset in Times of Crisis: Associations Between Father Involvement and Daughters' Sexual and Reproductive Health Outcomes.

Social work in public health·2026

Related Experiment Video

Updated: Feb 2, 2026

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience
09:51

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience

Published on: December 4, 2023

1.7K

Implementing value assessment in oncology practice: A single-center experience.

Katherine Saunders1, Mary S Mably2, Sara S Shull2

  • 11 Augusta University Medical Center, Augusta, GA, USA.

Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners
|November 29, 2018
PubMed
Summary

Rising cancer treatment costs challenge value-based care. A new tool piloted in advanced non-small cell lung cancer found atezolizumab offered the best value among immune checkpoint inhibitors.

Keywords:
Immunotherapynon-small cell lung canceroncologyvalue

More Related Videos

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
03:43

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

757
Practical Methodology of Cognitive Tasks Within a Navigational Assessment
05:19

Practical Methodology of Cognitive Tasks Within a Navigational Assessment

Published on: June 1, 2015

14.0K

Related Experiment Videos

Last Updated: Feb 2, 2026

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience
09:51

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience

Published on: December 4, 2023

1.7K
Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
03:43

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

757
Practical Methodology of Cognitive Tasks Within a Navigational Assessment
05:19

Practical Methodology of Cognitive Tasks Within a Navigational Assessment

Published on: June 1, 2015

14.0K

Area of Science:

  • Oncology
  • Health Economics
  • Clinical Decision Making

Background:

  • Increasing cancer treatment costs in the US are not consistently linked to better patient outcomes.
  • Existing value assessment tools face implementation challenges in clinical practice.
  • Value-based decision-making is difficult to integrate into routine oncology care.

Purpose of the Study:

  • To develop and pilot a novel value-based tool for cancer treatment decisions.
  • To inform clinicians and patients about the value of different cancer therapies.
  • To address the need for practical implementation of value assessment in oncology.

Main Methods:

  • Evaluation of existing value assessment frameworks.
  • Development of a new value-based tool by the Carbone Cancer Center.
  • Pilot testing of the tool in second-line metastatic or advanced non-small cell lung cancer (NSCLC).
  • Assessment of immune checkpoint inhibitors: nivolumab, atezolizumab, and pembrolizumab.

Main Results:

  • The pilot study identified atezolizumab as the best value among the evaluated immune checkpoint inhibitors in the specified NSCLC patient population.
  • The tool's application provided insights into the comparative value of different treatment options.
  • Challenges and opportunities for refinement were identified during the pilot phase.

Conclusions:

  • The developed value-based tool shows promise for informing clinical and patient decisions in oncology.
  • Atezolizumab demonstrated superior value compared to nivolumab and pembrolizumab in second-line advanced NSCLC.
  • The tool requires further refinement for broader application across various cancer types.