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Updated: Feb 2, 2026

A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle
Published on: January 11, 2018
Trabecular structural changes in the mandibular condyle caused by degenerative osteoarthritis: a comparative study by
Saadettin Kayipmaz1, Saliha Akçay2, Ömer Said Sezgin2
1Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Karadeniz Technical University, Farabi Street No. 64, 61080, Ortahisar/Trabzon, Turkey. kayipmaz@ktu.edu.tr.
Temporomandibular osteoarthritis alters condylar bone structure. Fractal analysis revealed significant differences in trabecular bone patterns between patients with this condition and healthy individuals.
Area of Science:
- Dental sciences
- Orthopedics
- Radiology
Background:
- Temporomandibular osteoarthritis (TMOA) leads to pain and functional impairment.
- Advanced TMOA can cause significant destruction of joint cartilage and bone structure.
Purpose of the Study:
- To investigate alterations in condylar trabecular bone structure in patients with TMOA.
- To compare bone structure between TMOA patients and healthy controls.
Main Methods:
- Utilized cone-beam computed tomography (CBCT) images.
- Applied fractal dimensional analysis with a box-counting method.
- Compared 35 TMOA patients with 35 healthy individuals.
Main Results:
- Average fractal dimensions differed significantly between groups (TMOA: 1.18, Healthy: 1.23).
- The observed difference was statistically significant (p ≤ 0.05).
Conclusions:
- Findings suggest TMOA involves osteoporotic changes in subchondral trabecular bone, not typically visible radiographically.
- Bone destruction and remodeling on the condyle surface, visible radiographically, are also associated with TMOA.
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