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Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension
Published on: March 17, 2022
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Unexpected postpneumonectomy exertion-induced acute right heart failure
Jacopo Colombo1, Iryna Arendar2, Ugo Pastorino3
11 Department of CardioThoracoVascular Anesthesia and Intensive Care, Niguarda Hospital, Milan, Italy.
Tumori
|November 29, 2018
Summary
Preoperative stress echocardiography can identify patients at risk for right heart failure after lung surgery. This method aids in assessing surgical suitability and preventing postoperative complications.
Area of Science:
- Cardiology
- Thoracic Surgery
- Pulmonary Medicine
Background:
- Accurate preoperative evaluation is crucial for thoracic surgery to minimize serious side effects.
- Standard preoperative assessments may not identify all patients at risk for postoperative complications.
Observation:
- A patient developed acute right heart failure (ARHF) and pulmonary hypertension post-pneumonectomy despite passing standard preoperative evaluations.
- Sildenafil administration led to clinical and echocardiographic improvement in the patient's ARHF.
Findings:
- Preoperative stress echocardiography can quantify exercise-induced right ventricle ejection fraction reduction.
- This technique identifies asymptomatic patients at risk for postoperative ARHF.
Implications:
- Stress echocardiography offers adjunctive value to cardiopulmonary exercise testing for major lung resection candidates.
- Identifying at-risk patients preoperatively can improve surgical outcomes and patient management.
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