Related Experiment Video
Updated: Jun 22, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Case for diagnosis. Ulcerated intradermal nevus simulating Sister Mary Joseph's nodule
Luísa Groba Bandeira1, Juliana Uchiyama1, Neusa Yuriko Sakai Valente1
1Dermatology Service, Hospital do Servidor Público do Estado de São Paulo, São Paulo (SP), Brazil.
Abstract:
We report a case of a 76-year-old patient with a history of recent weight loss and ulcerated umbilical nodular lesion. Initially, we considered the diagnostic hypothesis of Sister Mary Joseph's nodule. However, histopathological evaluation revealed that it was an ulcerated intradermal nevus. We perform a brief review of umbilical nodules.
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