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Related Experiment Video

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Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children &#8211; Working Memory (CABC-WM)
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Acute acalculous cholecystitis in children.

Dimitri Poddighe1, Vitaliy Sazonov1

  • 1Department of Medicine, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.

World Journal of Gastroenterology
|November 30, 2018
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Summary

Acute acalculous cholecystitis (AAC) in children often occurs without gallstones, frequently linked to viral infections and chronic immune disorders. This review covers its epidemiology, causes, and management in pediatric patients.

Keywords:
Acute acalculous cholecystitisChildrenViral biliary disorders

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Area of Science:

  • Pediatric Gastroenterology
  • Hepatology
  • Infectious Diseases

Background:

  • Acute acalculous cholecystitis (AAC) is gallbladder inflammation without gallstones.
  • AAC accounts for 50-70% of pediatric acute cholecystitis cases.
  • Historically seen in critically ill patients, pediatric AAC is now linked to infections and chronic diseases.

Purpose of the Study:

  • To review the epidemiology of pediatric AAC.
  • To discuss the etiology, pathophysiology, and clinical management of AAC in children.

Main Methods:

  • Literature review of reported pediatric AAC cases.
  • Analysis of epidemiological data, causes, and treatment strategies.

Main Results:

  • Pediatric AAC is frequently associated with viral infections (EBV, HAV).
  • Underlying chronic diseases, especially immune-mediated disorders, are implicated.
  • Management strategies are discussed based on literature findings.

Conclusions:

  • Pediatric AAC has diverse etiologies, including infections and immune disorders.
  • Understanding these factors is crucial for effective clinical management.
  • Further research may elucidate specific pathogenic mechanisms and optimize treatment.