B cells latently infected with murine gammaherpesvirus 68 (MHV-68) are present in the mouse thymus-A step toward

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Tomoyoshi Yamano1, Madlen Steinert1, Beatrix Steer2,3,4

  • 1Institute for Immunology, Ludwig-Maximilians-University Munich, Munich, Germany.

European Journal of Immunology
|November 30, 2018
PubMed

We show that latently gammaherpesvirus-infected B cells are present in the thymus. This could result in a functional T-cell tolerance against certain viral epitopes. It is conceivable that also antigens from other viruses or pathogens may be conveyed to the thymus for their immune evasion.

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