Antroalbocin A, an Antibacterial Sesquiterpenoid from Higher Fungus Antrodiella albocinnamomea
1School of Pharmaceutical Sciences , South-Central University for Nationalities , Wuhan 430074 , China.
Organic Letters
|November 30, 2018
Abstract:
Antroalbocin A (1), a sesquiterpenoid possessing a bridged tricyclic system, was isolated from cultures of the higher fungus Antrodiella albocinnamomea (Basidiomycota). The structure with the absolute configuration was determined by extensive spectroscopic methods and single-crystal X-ray diffraction. A plausible biosynthetic pathway for 1 was proposed. Compound 1 was found to inhibit Staphylococcus aureus with an MIC value of 169 μM.


