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Updated: Feb 1, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
Published on: October 17, 2025
Leukemia cutis in acute myeloid leukemia signifies a poor prognosis
Jolie A Krooks1, Angela G Weatherall2
1Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, USA.
Abstract:
Leukemia cutis (LC) is a rare neoplastic infiltration of the skin or subcutaneous tissue by leukemic cells. Because it correlates with sites of additional extramedullary involvement, it typically portends a poor prognosis. Although most cases of LC present concurrently with bone marrow infiltration, skin findings may precede systemic involvement in some cases; thus, early detection by dermatologists is essential. We report a case of a 66-year-old man who was diagnosed with acute myeloid leukemia (AML) based on the cutaneous presentation of LC.
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