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Published on: January 23, 2019
Effect of balloon guide catheter utilization on contact aspiration thrombectomy
Dong-Hun Kang1, Byung Moon Kim2, Ji Hoe Heo3
1Departments of1Neurosurgery and Radiology.
Insights
The use of a balloon guide catheter (BGC) in contact aspiration thrombectomy (CAT) for acute stroke significantly improves recanalization rates. BGC utilization is independently associated with successful reperfusion and better functional outcomes in stroke patients.
Area of Science:
- Neuroendovascular therapy
- Cerebrovascular diseases
- Interventional neurology
Background:
- Contact aspiration thrombectomy (CAT) is a primary treatment for acute stroke due to large vessel occlusion.
- The role of balloon guide catheters (BGC) in CAT has not been previously established.
- Evaluating BGC impact on recanalization and functional outcomes is crucial for optimizing stroke treatment.
Purpose of the Study:
- To investigate the association between balloon guide catheter (BGC) use and recanalization success in contact aspiration thrombectomy (CAT).
- To determine if BGC utilization in CAT impacts good functional outcomes for acute stroke patients.
- To compare procedural metrics between CAT with and without BGC.
Main Methods:
- Retrospective analysis of patients undergoing first-line CAT for anterior circulation large vessel occlusion.
- Dichotomization of patients into groups with and without BGC utilization.
- Comparison of recanalization rates, procedural times, and functional outcomes between the two groups.
Main Results:
- Balloon guide catheter (BGC) use was associated with fewer CAT passes and shorter puncture-to-recanalization times.
- BGC utilization led to significantly higher final (89.2% vs 72.8%) and first-pass (24.2% vs 8.1%) recanalization rates.
- BGC group had lower rates of additional thrombolytics and distal embolization.
Conclusions:
- Balloon guide catheter (BGC) utilization significantly enhances both first-pass and final recanalization rates in CAT.
- BGC use is independently associated with achieving successful recanalization and good functional outcomes after acute stroke.
- Incorporating BGC in CAT procedures may improve treatment efficacy for acute ischemic stroke.
Objective:
The role of the balloon guide catheter (BGC) has not been evaluated in contact aspiration thrombectomy (CAT) for acute stroke. Here, the authors aimed to test whether the BGC was associated with recanalization success and good functional outcome in CAT.
Methods:
All patients who had undergone CAT as the first-line treatment for anterior circulation intracranial large vessel occlusion were retrospectively identified from prospectively maintained registries for six stroke centers. The patients were dichotomized into BGC utilization and nonutilization groups. Clinical findings, procedural details, and recanalization success rates were compared between the two groups. Whether the BGC was associated with recanalization success and functional outcome was assessed.
Results:
A total of 429 patients (mean age 68.4 ± 11.4 years; M/F ratio 215:214) fulfilled the inclusion criteria. A BGC was used in 45.2% of patients. The overall recanalization and good outcome rates were 80.2% and 52.0%, respectively. Compared to the non-BGC group, the BGC group had a significantly reduced number of CAT passes (2.6 ± 1.6 vs 3.4 ± 1.5), shorter puncture-to-recanalization time (56 ± 27 vs 64 ± 35 minutes), lower need for the additional use of thrombolytics (1.0% vs 8.1%), and less embolization to a distal or different site (0.5% vs 3.4%). The BGC group showed significantly higher final (89.2% vs 72.8%) and first-pass (24.2% vs 8.1%) recanalization success rates. After adjustment for potentially associated factors, BGC utilization remained independently associated with recanalization (OR 4.171, 95% CI 1.523-11.420) and good functional outcome (OR 2.103, 95% CI 1.225-3.612).
Conclusions:
BGC utilization significantly increased the final and first-pass recanalization rates and remained independently associated with recanalization success and good functional outcome.
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