Painful left bundle branch block syndrome treated with his bundle pacing
Juan F Viles-Gonzalez1, Indrajeet Mahata1, Elad Anter2
1Tulane University, United States of America.
Journal of Electrocardiology
|December 1, 2018
Summary
Painful Left Bundle Branch Block (LBBB) Syndrome, though under-recognized, can be effectively treated with His bundle pacing. This case report shows complete chest pain resolution, offering a new treatment option.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Case Reports
Background:
- Painful Left Bundle Branch Block (LBBB) Syndrome is a rare and challenging clinical entity.
- Diagnosis and treatment strategies for this syndrome remain poorly defined.
- Previous attempts using right ventricular pacing have yielded inconsistent results.
Observation:
- A case report details a patient experiencing painful LBBB Syndrome.
- The patient presented with symptoms suggestive of this under-recognized condition.
- Standard pacing methods had not been previously explored or reported for this specific syndrome.
Findings:
- His bundle pacing (HBP) was implemented as a novel therapeutic approach.
- The patient experienced complete resolution of chest pain following HBP.
- This represents the first reported instance of successful chest pain management using HBP in painful LBBB Syndrome.
Implications:
- His bundle pacing emerges as a promising alternative treatment for painful LBBB Syndrome.
- This approach may offer significant symptom relief for affected patients.
- Further research is warranted to validate HBP as a standard treatment for this condition.
Related Concept Videos
Pain
1.4K
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
1.4K
Block Diagram Reduction
561
The process of deriving the transfer function of a control system often involves reducing its block diagram to a single block. This simplification can be achieved through a series of strategic operations, including relocating branch points and comparators. These operations preserve the overall function of the system while allowing for easier manipulation and combination of blocks.
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
561
Elements of Block Diagrams
705
Block diagrams serve as a visual representation of the input-output relationships within a system. An illustrative example is a heating system, where the set temperature activates the furnace to warm the room to the desired level. Block diagrams are versatile, modeling linear systems through Laplace transform variables and nonlinear systems using time domain variables.
A block diagram typically includes essential elements such as comparators, blocks, and feedback loops. Each of these elements...
A block diagram typically includes essential elements such as comparators, blocks, and feedback loops. Each of these elements...
705
Mass Spectrometry: Branched Alkane Fragmentation
1.7K
This lesson delves into the mass spectrometry of branched alkane fragmentation. Branched alkanes possess secondary or tertiary carbon atoms, which generate relatively stable carbocations if the cleavage occurs at the branching point. The high stability of carbocations drives the instant fragmentation of branched alkanes. Accordingly, the branched alkane's molecular ion peak is very weak or invisible in the mass spectra, especially in comparison to a linear alkane.
1.7K
Generation of Straight or Branched Actin Filaments
3.8K
The straight or branched structure formation of actin filaments is controlled by nucleating proteins such as the formins and Arp2/3 complex. Formin-mediated assembly results in straight filaments, whereas Arp2/3 protein complex-mediated assembly results in branched actin filaments.
Arp2/3 Complex
Arp2/3 complex is a seven-subunit complex consisting of two proteins similar to actin- Arp2 and Arp3, and five other subunits that help keep Arp2 and Arp3 inactive. When required, the complex is...
Arp2/3 Complex
Arp2/3 complex is a seven-subunit complex consisting of two proteins similar to actin- Arp2 and Arp3, and five other subunits that help keep Arp2 and Arp3 inactive. When required, the complex is...
3.8K
Nephrotic Syndrome I : Introduction
641
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
641


