Related Experiment Video
Updated: Feb 1, 2026

fMRI Mapping of Brain Activity Associated with the Vocal Production of Consonant and Dissonant Intervals
Published on: May 23, 2017
Measuring abnormal intrinsic brain activities in patients with retinal detachment using amplitude of low-frequency
Hong-Hua Kang1, Yong-Qiang Shu2, Lin Yang1
1a Department of Ophthalmology , The First Affiliated Hospital of Nanchang University , Nanchang , Jiangxi , China.
Objective:
The targets of this study were to access the alternations of spontaneous brain activity in RD patients by amplitude of low-frequency fluctuation (ALFF) method and to explore their relationships with clinical behavioral performance.
Methods:
A total of 20 patients with RD (6 males and 14 females), and 20 healthy controls (HCs) (6 males and 14 females) were recruited, and were matched in sex and age. All participants finished the functional magnetic resonance imaging (fMRI) scanning. We applied the ALFF method to detect the spontaneous brain activity. Receiver operating characteristic (ROC) curve was applied to distinguish RD Patients from HCs.
Results:
RD patients showed decreased ALFF values in the right occipital lobe and right medial frontal gyrus and increased ALFF values in the right frontal superior orbital and left inferior temporal gyrus when compared with HCs. In RD patients, we did not find any relationship between the mean ALFF values and the clinical behavioral performances.
Conclusion:
The RD patients exhibited abnormal spontaneous brain activity in vision and vision related brain regions, which might explore potential pathological mechanism of acute vision loss in RD patients.
Related Concept Videos
Intrinsically Disordered Proteins
The Resting Membrane Potential
Abnormal Proliferation
Resting Membrane Potential
The Inside of a Neuron is More Negative
The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...
Pulse amplitude and quality
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
Resting Potential Decay
At rest, the K+ is the main ion that moves across the membrane...

