Related Experiment Video

Updated: Feb 1, 2026

Incorporating Target Protein Structure Flexibility and Dynamics in Computational Drug Discovery Using Ensemble-Based Docking Analysis
08:49

Incorporating Target Protein Structure Flexibility and Dynamics in Computational Drug Discovery Using Ensemble-Based Docking Analysis

Published on: June 20, 2025

1.2K

Discovery of selective inhibitors for cyclic AMP response element-binding protein: a combined ligand and

Iqra Muneer1, Muhammad T Ul Qamar2, Kishver Tusleem3

  • 1School of Life Sciences, University of Science and Technology of China, Hefei.

Anti-Cancer Drugs
|December 1, 2018
PubMed

More Related Videos

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

11.8K
A Protocol for Computer-Based Protein Structure and Function Prediction16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

69.8K

Related Concept Videos

Ligand Binding and Linkage00:49

Ligand Binding and Linkage

Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
5.6K
Ligand Binding and Linkage00:49

Ligand Binding and Linkage

4.1K
Ligand Binding Sites02:40

Ligand Binding Sites

Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
15.1K
Ligand Binding Sites02:40

Ligand Binding Sites

8.8K
Frequency Response of Op Amp Circuits01:20

Frequency Response of Op Amp Circuits

Operational amplifiers (op-amp) are used in signal conditioning, filtering, or for performing mathematical operations such as addition, subtraction, integration, and differentiation. The frequency response of an op-amp is an important aspect that describes how the gain of the amplifier varies with frequency.
Frequency Response and Gain:
The gain of the op-amp, A(ω), is not a constant but a function of the input signal frequency. An op-amp can maintain a constant gain at low frequencies, known...
676
Protein and Protein Structure02:15

Protein and Protein Structure

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme...
87.6K