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Probiotics on Pediatric Functional Gastrointestinal Disorders

Anna Pärtty1,2, Samuli Rautava3,4, Marko Kalliomäki5,6

  • 1Department of Pediatrics, University of Turku, 20521 Turku, Finland. aklein@utu.fi.

Nutrients
|December 2, 2018
PubMed

Insights

Probiotics show limited efficacy for childhood functional gastrointestinal disorders. Lactobacillus reuteri DSM 17938 may help breastfed infants with colic, but more research is needed for other conditions.

Area of Science:

  • Pediatric Gastroenterology
  • Microbiome Research
  • Probiotic Therapeutics

Background:

  • Childhood functional gastrointestinal disturbances are linked to gut microbiota changes.
  • Probiotics offer potential therapeutic and preventive strategies.

Purpose of the Study:

  • To review evidence on probiotic efficacy for pediatric functional abdominal pain disorders, functional constipation, and infantile colic.

Main Methods:

  • Systematic review of current scientific literature.
  • Evaluation of studies on single probiotic strains, combinations, and synbiotics.

Main Results:

  • No specific probiotic strain, combination, or synbiotic is currently recommended for pediatric irritable bowel syndrome, functional abdominal pain, or functional constipation.
  • Lactobacillus reuteri DSM 17938 shows potential for managing colic in breastfed infants.
  • Limited data exists for other probiotic interventions in infantile colic.

Conclusions:

  • Current evidence does not support broad probiotic recommendations for most pediatric functional gastrointestinal disorders.
  • Lactobacillus reuteri DSM 17938 is a potential option for infantile colic in breastfed infants.
  • Further research is required to establish the efficacy of various probiotics and synbiotics.

Keywords:
functional abdominal pain disordersfunctional constipationfunctional gastrointestinal disordersinfantile colicprobiotics

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