Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Self-Discrepancy Theory02:45

Self-Discrepancy Theory

18.9K
One influential perspective on what motivates people's behavior is detailed in Tory Higgin's self-discrepancy theory (Higgins, 1987). He proposed that people hold disagreeing internal representations of themselves that lead to different emotional states.  
18.9K
Scanning Electron Microscopy01:07

Scanning Electron Microscopy

5.5K
A scanning electron microscope (SEM) is used to study the surface features of a sample by using an electron beam that scans the sample surface in a two-dimensional manner. Typically, areas between ~1 centimeter to 5 micrometers in width can be imaged. SEM can be used to image bacteria, viruses, tissues as well as larger samples like insects. Conventional SEM gives a magnification ranging from 20X to 30,000X and spatial resolution of 50 to 100 nanometers.
Fundamental Principles
Accelerated...
5.5K
Self-Discrepancy and Its Effects01:29

Self-Discrepancy and Its Effects

318
Self-discrepancy theory explains how people compare their actual self to their ideal and ought selves and how mismatches between these self-guides can lead to emotional distress. Developed by E. Tory Higgins, the theory distinguishes among three components of self-concept: the actual self, the ideal self, and the ought self. These refer respectively to how individuals perceive themselves, how they aspire to be, and how they believe they are obligated to be. Emotional well-being, self-esteem,...
318
Leaky Scanning02:28

Leaky Scanning

5.7K
During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
5.7K
The Sense of Self: Reflected Self-Appraisal and Social Comparison02:57

The Sense of Self: Reflected Self-Appraisal and Social Comparison

56.1K
According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
56.1K
Common Ion Effect03:24

Common Ion Effect

46.7K
Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Châtelier’s principle. Consider the dissolution of silver iodide:
46.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Maternal Cardiac Disease and Congenital Heart Disease Risk in Offspring.

JAMA network open·2026
Same author

Impact of preoperative femoral vein ultrasound localization on puncture success and procedural complications during radiofrequency catheter ablation for atrial fibrillation: A multicenter study.

Medicine·2026
Same author

BMPR2 affects valve development via ECM-receptor interaction in zebrafish.

Frontiers in cell and developmental biology·2026
Same author

Employment of the Ascending Aortic Volume as a Predictor of Adverse Outcomes in Patients With Bicuspid Aortic Valve Disease.

Reviews in cardiovascular medicine·2026
Same author

Reply to the Letter to the Editor "Sex imbalance in a large Fontan cohort: Biological reality or marker of inequitable care?"

Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology·2026
Same author

Widening effect of SICM topography measurement based on electrolyte concentration gradient with dual-barrel pipette.

Micron (Oxford, England : 1993)·2026

Related Experiment Video

Updated: Feb 1, 2026

Focussed Ion Beam Milling and Scanning Electron Microscopy of Brain Tissue
08:57

Focussed Ion Beam Milling and Scanning Electron Microscopy of Brain Tissue

Published on: July 6, 2011

28.7K

A fast scanning ion conductance microscopy imaging method using compressive sensing and low-discrepancy sequences.

Zhiwu Wang1, Jian Zhuang1, Zijun Gao1

  • 1Key Laboratory of Education Ministry for Modern Design Rotor-Bearing System, Xi'an Jiaotong University, Xi'an 710049, China.

The Review of Scientific Instruments
|December 4, 2018
PubMed
Summary
This summary is machine-generated.

This study introduces a Compressed Sensing (CS)-based scanning method to accelerate Scanning Ion Conductance Microscopy (SICM) imaging. The new CS-based mode significantly speeds up imaging without compromising image quality, enabling better study of dynamic biological processes.

More Related Videos

Targeted Studies Using Serial Block Face and Focused Ion Beam Scan Electron Microscopy
09:09

Targeted Studies Using Serial Block Face and Focused Ion Beam Scan Electron Microscopy

Published on: August 10, 2019

9.7K
Thermal Scanning Conductometry TSC as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels
10:01

Thermal Scanning Conductometry TSC as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels

Published on: January 23, 2018

8.1K

Related Experiment Videos

Last Updated: Feb 1, 2026

Focussed Ion Beam Milling and Scanning Electron Microscopy of Brain Tissue
08:57

Focussed Ion Beam Milling and Scanning Electron Microscopy of Brain Tissue

Published on: July 6, 2011

28.7K
Targeted Studies Using Serial Block Face and Focused Ion Beam Scan Electron Microscopy
09:09

Targeted Studies Using Serial Block Face and Focused Ion Beam Scan Electron Microscopy

Published on: August 10, 2019

9.7K
Thermal Scanning Conductometry TSC as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels
10:01

Thermal Scanning Conductometry TSC as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels

Published on: January 23, 2018

8.1K

Area of Science:

  • Biophysics
  • Microscopy techniques
  • Signal processing

Background:

  • Scanning Ion Conductance Microscopy (SICM) offers high-resolution, non-contact imaging of biological samples in physiological conditions.
  • The conventional hopping/backstep mode of SICM suffers from slow imaging speeds, limiting the observation of dynamic biological processes.

Purpose of the Study:

  • To develop and validate a novel undersampled scanning method for SICM based on Compressed Sensing (CS) theory.
  • To overcome the speed limitations of traditional SICM hopping/backstep modes for dynamic biological studies.

Main Methods:

  • Implementation of a CS-based scanning mode utilizing three distinct undersampling patterns: random and two low-discrepancy sequences.
  • Acquisition of undersampled data with varying undersampling ratios.
  • Reconstruction of images using the TVAL3 algorithm.

Main Results:

  • The CS-based scanning mode effectively accelerates SICM imaging speed without sacrificing image quality compared to conventional methods.
  • Low-discrepancy sampling patterns demonstrated superior reconstruction performance over random patterns at identical undersampling ratios.
  • CS-based SICM successfully imaged samples with varying topographic complexities at increased speeds.

Conclusions:

  • The CS-based scanning mode represents a significant advancement for SICM, enabling faster imaging of dynamic biological samples.
  • Low-discrepancy sequences are recommended for sampling patterns in CS-based SICM for enhanced reconstruction accuracy.
  • This technique broadens the scope of SICM for studying time-dependent biological phenomena.