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Neurotoxicity of the antibiotics: A comprehensive study
Naghmeh Javanshir Rezaei1, Amir Mohammad Bazzazi2, Seyed Ahmad Naseri Alavi3
1Department of Microbiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Neurology India
|December 4, 2018
Summary
Antibiotics can cause serious neurological side effects like seizures and nerve damage. This review details common neurotoxic adverse events from frequently used antibiotics.
Area of Science:
- Pharmacology
- Neuroscience
- Clinical Medicine
Background:
- Antibiotics are essential in treating bacterial infections.
- Neurotoxic adverse events are a significant concern with antibiotic use.
- Common neurological side effects include seizures, encephalopathy, and neuropathy.
Purpose of the Study:
- To review the most common and important neurotoxic adverse effects of antibiotics.
- To highlight neurological risks associated with routine antibiotic therapy.
Main Methods:
- Literature review of antibiotic-induced neurotoxicity.
- Analysis of case reports and clinical studies.
- Synthesis of data on common neurotoxic effects.
Main Results:
- Antibiotics can cause seizures, encephalopathy, optic neuropathy, and peripheral neuropathy.
- Exacerbation of myasthenia gravis is another critical neurotoxic effect.
- Various antibiotic classes are associated with distinct neurological adverse events.
Conclusions:
- Awareness of antibiotic-induced neurotoxicity is crucial for clinicians.
- Monitoring for neurological symptoms during antibiotic treatment is recommended.
- Understanding these risks aids in safe and effective antibiotic prescribing.
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