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Hemiballism in multiple sclerosis.

D Riley1, A E Lang

  • 1Movement Disorders Clinic, Toronto Western Hospital, Ontario, Canada.

Movement Disorders : Official Journal of the Movement Disorder Society
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

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Hemiballism, a rare movement disorder, is documented in a definite multiple sclerosis case. A subthalamic nucleus lesion on MRI confirmed the diagnosis, clarifying previous uncertain reports.

Area of Science:

  • Neurology
  • Neuroscience
  • Movement Disorders

Background:

  • Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system.
  • Hemiballism, characterized by involuntary, violent, and large-amplitude limb movements, is an exceptionally rare manifestation in MS.
  • Previous reports of hemiballism in MS patients often lacked definitive diagnostic evidence.

Observation:

  • This study presents a case of a patient diagnosed with definite multiple sclerosis.
  • The patient exhibited clear symptoms of hemiballism, which were captured on videotape.
  • Magnetic resonance imaging (MRI) revealed a demyelinating plaque in the subthalamic nucleus contralateral to the affected limbs.

Findings:

  • The findings confirm a direct correlation between a specific brain lesion location (subthalamic nucleus) and the occurrence of hemiballism in a confirmed MS patient.

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  • This case provides strong evidence supporting hemiballism as a potential, albeit rare, clinical manifestation of multiple sclerosis.
  • The presence of a contralateral subthalamic nucleus lesion is identified as a key diagnostic marker.

    • Implications:

    • This case enhances the understanding of the diverse neurological presentations of multiple sclerosis.
    • It highlights the importance of advanced neuroimaging in diagnosing rare movement disorders associated with MS.
    • Accurate diagnosis of hemiballism in MS can guide appropriate patient management and treatment strategies.