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Updated: Feb 1, 2026
Plaquing of Herpes Simplex Viruses
Published on: November 5, 2021
Herpes Simplex Virus 1 and 2 in Herpes Genitalis: A Polymerase Chain Reaction-Based Study from Kerala
Rani Mathew1, Bangalath Najeem2, Kunjumani Sobhanakumary1
1Department of Dermatology and Venereology, Government T D Medical College, Alappuzha, Kerala, India.
Background:
Herpes genitalis is an ulcerating sexually transmitted infection, the clinical importance of which lies in its ability to produce painful and recurrent disease in addition to its potential role as a cofactor in acquisition and transmission of human immunodeficiency virus. In recent years, there are increasing reports of genital herpes due to herpes simplex virus (HSV)-1 from various parts of the world. Molecular diagnostic methods such as polymerase chain reaction (PCR) have got both diagnostic and prognostic significance in genital herpes.
Aims:
The present study was designed to identify the viral serotype in herpes genitalis patients in our locality, using PCR.
Materials And Methods:
The specimens from forty herpes genitalis patients were subjected to nested PCR and results were evaluated.
Results:
PCR was positive for HSV in 83% of cases, of which 58% were due to HSV-1. HSV-2 accounted for maximum number of recurrent herpes.
Limitation:
Higher sample size would have been more representative.
Conclusion:
A rising trend of type 1 HSV was observed in herpes genitalis in south India probably due to increasing practice of orogenital sex.
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