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Updated: Feb 1, 2026

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
Initial experience with uniportal video-assisted thoracic surgery esophagectomy
Dania Nachira1, Elisa Meacci1, Maria Giovanna Mastromarino1
1Department of General Thoracic Surgery, Catholic University of Sacred Heart, Fondazione Policlinico Universitario "A.Gemelli", Rome, Italy.
Uniportal video-assisted thoracic surgery (VATS) esophagectomy is a safe and effective minimally invasive option for esophageal cancer. This technique shows promising results in terms of reduced pain and improved cosmetic outcomes compared to multiportal VATS.
Area of Science:
- Thoracic Surgery
- Minimally Invasive Surgery
- Surgical Oncology
Background:
- Multiportal thoracoscopic esophagectomy is a standard minimally invasive procedure.
- Limited data exists on uniportal VATS esophagectomy.
- This study evaluates the preliminary experience with uniportal VATS esophagectomy.
Purpose of the Study:
- To evaluate the short-term outcomes of uniportal VATS esophagectomy.
- To compare uniportal VATS with multiportal VATS for esophagectomy.
- To assess perioperative mortality, complications, oncological radicality, pain, and cosmetic results.
Main Methods:
- Retrospective review of 12 patients undergoing uniportal VATS esophagectomy (McKeown technique) from December 2016 to November 2017.
- Data collected included perioperative outcomes, complications, and oncological results.
- Outcomes were evaluated based on collected clinical data.
Main Results:
- Mean operative time was 104.67 minutes, with a mean of 10.44 thoracic nodes removed.
- No local recurrence was observed; 83.3% of patients were alive with no evidence of disease at follow-up.
- Complications included anastomotic leak (16.7%) and chylothorax (8.3%); mean postoperative pain was low (1.92/10).
Conclusions:
- Uniportal VATS esophagectomy is a safe, feasible, and effective alternative to multiportal VATS.
- It offers potential advantages in reduced postoperative pain and improved cosmetic outcomes.
- Further studies with longer follow-up are needed to confirm these findings.
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