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Neurocognitive function in moderate-severe pediatric atopic dermatitis: A case-control study.

Lacey L Kruse1,2, Ahuva Cices2, Anna B Fishbein3

  • 1Division of Dermatology, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois.

Pediatric Dermatology
|December 4, 2018
PubMed
Summary
This summary is machine-generated.

Children with atopic dermatitis (AD) did not show a higher prevalence of attention deficit hyperactivity disorder (ADHD). However, they did exhibit increased inattention and other ADHD-associated behaviors.

Keywords:
atopic dermatitisattention deficit hyperactivity disorderbehaviorinattentionneurocognitivesleepsleep disturbance

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Area of Science:

  • Pediatric Dermatology
  • Neurodevelopmental Disorders
  • Child Psychology

Background:

  • Previous studies suggest a link between atopic dermatitis (AD) and attention deficit hyperactivity disorder (ADHD).
  • AD symptoms like poor sleep and itching may contribute to ADHD-like behaviors.

Purpose of the Study:

  • To investigate the prevalence of ADHD in children with moderate-to-severe AD.
  • To compare ADHD symptoms and behaviors in children with AD versus healthy controls.

Main Methods:

  • A case-control study involving children aged 6-17 years with moderate/severe AD and age/sex-matched healthy controls.
  • Screening for ADHD using parent-completed Vanderbilt assessments.

Main Results:

  • No significant difference in ADHD screening rates between children with AD (11.7%) and controls (5.56%).
  • Children with AD were more likely to display inattention and other ADHD-associated behaviors compared to controls.

Conclusions:

  • The study cohort with moderate-to-severe AD did not show a significantly increased prevalence of ADHD.
  • Children with moderate-to-severe AD exhibited increased neurocognitive symptoms, particularly inattention.