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Undernutrition and growth in the developing world

Jasreena K Nijjar1, Diane Stafford2

  • 1Division of Pediatric Endocrinology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

Current Opinion in Endocrinology, Diabetes, and Obesity
|December 4, 2018
PubMed

Insights

Millions of children globally remain stunted due to nutritional deficits. This review explores how nutrition impacts longitudinal bone growth and stunting in developing nations, highlighting areas for future research.

Area of Science:

  • Pediatric Nutrition
  • Growth and Development
  • Global Health

Background:

  • An estimated 150.8 million children under 5 years globally are stunted, with high prevalence in Asia and Africa.
  • Childhood stunting remains a significant public health challenge in low and middle-income countries (LMICs).

Purpose of the Study:

  • To review current knowledge on nutritional regulation of longitudinal bone growth in the developing world.
  • To summarize the impact of dietary macronutrients and micronutrients on child growth.

Main Methods:

  • Literature review of recent advances in understanding nutritionally sensitive growth regulators.
  • Prospective evaluations of specific dietary components' impact on growth.

Main Results:

  • Investigations into nutritionally sensitive regulators of growth have advanced.
  • Prospective evaluations are assessing the impact of specific dietary components on growth.

Conclusions:

  • Further research is needed to elucidate nutrition's impact on growth and stunting mechanisms.
  • Optimizing therapeutic strategies for at-risk or stunted children in LMICs requires further investigation.
Abstract

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