Related Experiment Video
Updated: Feb 1, 2026
02:09
Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
1.1K
Intravascular large B-cell lymphoma presenting with diffusely increased pulmonary fluorodeoxyglucose uptake without
Jayden Spencer1, Reginald Dusing1, Wendell Yap1
1Department of Radiology, Kansas University Hospital, 3901 Rainbow Blvd, MS 4032, Kansas City, KS, USA.
Radiology Case Reports
|December 5, 2018
Summary
A rare form of lymphoma, intravascular large B-cell lymphoma (IV-LBCL), can cause lung issues. This case highlights its presentation with respiratory failure and weight loss, confirmed by biopsy.
Area of Science:
- Oncology
- Pulmonology
- Pathology
Background:
- Intravascular large B-cell lymphoma (IV-LBCL) is an uncommon extranodal non-Hodgkin lymphoma.
- Pulmonary involvement by IV-LBCL can present insidiously, mimicking other inflammatory or infectious lung diseases.
Observation:
- A 60-year-old male presented with dyspnea, fever, and significant weight loss.
- Initial investigations revealed elevated inflammatory markers, anemia, and thrombocytopenia.
- FDG-PET scans showed increased lung uptake, but CT scans were unremarkable.
Findings:
- Excisional lung biopsy definitively diagnosed intravascular large B-cell lymphoma (IV-LBCL).
- The case underscores the diagnostic challenges of IV-LBCL presenting with pulmonary symptoms.
Implications:
- Early recognition of IV-LBCL is crucial for timely treatment and improved patient outcomes.
- This case emphasizes the importance of considering rare hematologic malignancies in the differential diagnosis of unexplained pulmonary symptoms and systemic illness.
Keywords:
ARDS, acute respiratory distress syndromeCTCT, computed tomographyCTA, computed tomography angiogramFDG, fluorodeoxyglucoseFDG-PETH&E, hematoxylin-eosinIV-LBCL, intravascular large B-cell lymphomaIntravascular large B-cell lymphomaLymphomaMIP, maximum intensity projectionPET, positron emission tomographyPulmonary uptakeMore Related Videos
![Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F3777.jpg&w=3840&q=50)
10:02Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
Published on: May 2, 2012
18.7K
07:13Phenotyping Mouse Pulmonary Function In Vivo with the Lung Diffusing Capacity
Published on: January 6, 2015
11.1K
Related Concept Videos
01:12Diffusion
218.6K
Diffusion is the passive movement of substances down their concentration gradients—requiring no expenditure of cellular energy. Substances, such as molecules or ions, diffuse from an area of high concentration to an area of low concentration in the cytosol or across membranes. Eventually, the concentration will even out, with the substance moving randomly but causing no net change in concentration. Such a state is called dynamic equilibrium, which is essential for maintaining overall...
218.6K
01:21Diffusion
6.4K
Diffusion is a type of passive transport. In passive transport, a substance tends to move from an area of high concentration to an area of low concentration until the concentration is equal across the space. For example, take the diffusion of substances through the air. When someone opens a perfume bottle in a room filled with people, the perfume is at its highest concentration in the bottle and is at its lowest at the edges of the room. The perfume vapor will diffuse, or spread away, from the...
6.4K
02:23Abnormal Proliferation
5.2K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
5.2K
01:18Increasing Function
394
An increasing function exhibits a rise in output values as input values increase. This behavior is depicted graphically as a curve or line that slopes upward from left to right. Such a function satisfies the condition that if x1 < x2, then f(x1) < f(x2), indicating that the function values grow with increasing inputs. This concept is fundamental in understanding growth trends across various domains, such as population dynamics, financial investments, or resource consumption.The...
394
01:25Increased Body Temperature
7.5K
A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
7.5K
01:17Increased pulse rate
1.2K
Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
1.2K