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Updated: Feb 1, 2026

Author Spotlight: RNAi Inheritance and ChIP in C. elegans
Published on: May 5, 2023
The Autosomal Dominant Inheritance of Hereditary Gingival Fibromatosis: A Case Report
Abstract:
Hereditary gingival fibromatosis (HGF) is a rare disorder characterized by progressive and varying degrees of gingival overgrowth. Oral manifestations vary from minimal to generalized enlargement, and HGF may occur as an isolated disorder or a feature of a syndrome. Unaesthetic appearance and functional impairment due to excessive gingival tissue dictate the need for surgical intervention. This article describes a family with three generations afflicted with a non-syndromic form of HGF with distinctive clinical, histological characteristics. Further, it highlights the need for genetic analysis and appropriate surgical technique to manage gingival enlargement and avoid recurrence.
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