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Related Experiment Videos

Jean-Christophe Dubus1, Mélisande Baravalle-Einaudi1, Sophia Bellulo1

  • 1Services de pédiatrie et pneumologie pédiatrique, hôpital de La Timone-Enfants et hôpital Nord, AP-HM, Aix-Marseille Université, Marseille, France.

La Revue Du Praticien
|December 5, 2018
PubMed
Summary
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Current evidence shows no inhaled treatments are recommended for acute viral bronchiolitis in infants. Studies indicate limited efficacy and potential side effects for most therapies, including beta-2 agonists and hypertonic saline.

Area of Science:

  • Pediatrics
  • Pulmonology
  • Infectious Diseases

Context:

  • Acute viral bronchiolitis is a common respiratory infection in infants.
  • Inhaled therapies are frequently administered despite a lack of robust evidence.
  • Practitioner use of these treatments is widespread.

Purpose:

  • To evaluate the efficacy of various inhaled treatments for acute viral bronchiolitis in infants.
  • To provide evidence-based recommendations on the use of inhaled therapies.

Summary:

  • Beta-2 agonists show no benefit and potential side effects.
  • Anticholinergic drugs and adrenaline are not recommended.
  • Corticosteroids are ineffective for acute treatment or preventing post-viral asthma.
  • Ribavirin is reserved for specific indications.
Keywords:
Bronchiolite aiguë du nourrissonPlace des traitements inhalés dans la bronchiolite aiguë du nourrisson

Related Experiment Videos

  • Hypertonic saline has accumulated negative studies and is not recommended.
  • Overall, no inhaled treatment is recommended for acute viral bronchiolitis as of 2016.
  • Impact:

    • Discourages the use of ineffective inhaled treatments in infants with bronchiolitis.
    • Promotes evidence-based clinical practice guidelines.
    • Reduces unnecessary medication exposure and potential adverse effects in infants.