[Factors and clinical forms of gastroesophageal reflux disease in adults]

Factors and clinical forms of gastroesophageal reflux disease in adults. Gastro-oesophageal reflux (GERD) is a common complaint. Factors involved in GERD are the antireflux barrier dysfunction, the oesophageal sensitivity disorders, impaired oesophageal clearance, the acid component of the refluxate, and impaired gastric emptying. Risk factors for GERD are hiatal hernia and obesity. Although heartburn or regurgitations are specific to characterize GERD, patients usually report a number of associated symptoms such as cough, eructation, globus, hiccups, chest pain, and sleep disturbances. Complications of GERD are oesophagitis, gastrointestinal haemorrhage, peptic stricture or Barrett's oesophagus.