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Hidradenitis suppurativa
1Service de colo-proctologie, institut de proctologie Léopold-Bellan, hôpital Saint-Joseph, Paris, France.
La Revue Du Praticien
|December 5, 2018
Summary
Hidradenitis Suppurativa (HS) is a chronic inflammatory skin condition causing painful nodules. Treatment involves antibiotics, biologics, surgery, and lifestyle changes for improved quality of life.
Area of Science:
- Dermatology
- Inflammatory Diseases
Background:
- Hidradenitis Suppurativa (HS), also known as Verneuil disease, is a chronic, inflammatory skin condition.
- It affects approximately 1% of the European population, primarily developing after puberty.
- HS is characterized by painful, recurrent nodules in apocrine gland-rich areas, significantly impairing quality of life.
Purpose of the Study:
- To provide an overview of Hidradenitis Suppurativa.
- To discuss the underlying mechanisms, associations, and treatment modalities for HS.
Main Methods:
- Literature review of HS pathogenesis, clinical presentation, and therapeutic strategies.
- Discussion of multimodal treatment approaches including medical and surgical interventions.
- Emphasis on adjuvant care and outcome evaluation.
Main Results:
- HS involves hair follicle occlusion and lympho-histiocytic inflammation.
- Associated factors include overweight, smoking, metabolic syndrome, and other inflammatory diseases.
- A multimodal treatment approach is essential for managing HS.
Conclusions:
- Effective management of HS requires a comprehensive strategy addressing inflammation, fibrotic lesions, and associated comorbidities.
- Antibiotics, biologics, and surgery form the cornerstone of treatment.
- Adjuvant care focusing on metabolic syndrome, weight management, and smoking cessation is crucial for patient outcomes.