Related Experiment Video
Updated: Feb 1, 2026

07:09
A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs
Published on: February 18, 2022
2.4K
Evaluating the Association Between the Three Different Ejection Fraction Measurement Techniques and Left Ventricle
Ednan Bayram1, Oktay Gulcu2, Ugur Aksu3
1Department of Cardiology, Atatürk University School of Medicine, Erzurum, Turkey.
The Eurasian Journal of Medicine
|December 6, 2018
Summary
The Simpson
Area of Science:
- Cardiology
- Echocardiography
- Cardiac Imaging
Background:
- Cardiovascular disease (CVD) prognosis relies on systolic function, measured by ejection fraction (EF).
- Left ventricular global strain (LVGS) shows superior predictivity for CVD diagnosis, prognosis, and staging compared to EF.
- Previous studies have not thoroughly investigated the correlation between different EF measurement methods and LVGS parameters.
Purpose of the Study:
- To analyze the association between three ejection fraction (EF) measurement methods and left ventricular global strain (LVGS).
- To determine which EF measurement method correlates best with LVGS.
- To evaluate the diagnostic utility of different EF methods for abnormal LVGS.
Main Methods:
- Echocardiography was performed on 62 patients (excluding those with atrial fibrillation or poor image quality).
- Three EF measurement techniques were employed: visual EF, Simpson's rule EF, and Teicholtz method.
- Statistical analysis was used to assess the correlation between EF measurements and LVGS parameters.
Main Results:
- A statistically significant association was found between visual EF, Simpson EF, and LVGS parameters (p<0.001).
- Simpson's rule EF demonstrated a good correlation with LVGS parameters (r=0.710).
- Visual EF showed a moderate correlation with LVGS parameters (r=0.44).
Conclusions:
- Simpson's rule ejection fraction (EF) measurement correlates better with left ventricular global strain (LVGS) than visual EF or the Teicholtz method.
- Simpson's rule EF offers a superior area under the curve for identifying abnormal LVGS.
- The study recommends using Simpson's rule EF for evaluating ventricular function due to its stronger correlation with LVGS.
Related Concept Videos
Measurements of Strain
2.6K
Strain quantifies the deformation of a material under force, typically measured as normal strain, which represents the change in length when compared with the original length. Electrical strain gauges are used for enhanced accuracy. These devices consist of a conductive wire mounted on a paper backing that adheres to the material's surface. These gauges operate on the piezoresistive effect, where the wire's electrical resistance changes in response to mechanical deformation. The strain...
2.6K
Global Climate Change
28.9K
Throughout its ~4.5 billion year history, the Earth has experienced periods of warming and cooling. However, the current drastic increase in global temperatures is well outside of the Earth’s cyclic norms, and evidence for human-caused global climate change is compelling. Paleoclimatology, the study of ancient climate conditions, provides ample evidence for human-caused global climate change by comparing recent conditions with those in the past.
28.9K
Anatomy of the Brain: Ventricles
9.0K
There are hollow fluid-filled cavities known as ventricles deep inside the human brain. There are two lateral ventricles, one in each cerebral hemisphere, and each has three different projections — the anterior, inferior, and posterior horns visible from the lateral side. A thin membrane called the septum pellucidum separates the two lateral ventricles. The slender third ventricle in the diencephalon is connected to each lateral ventricle via a channel called the interventricular foramen.
9.0K
Association Areas of the Cortex
9.4K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
9.4K
Associative Learning
1.3K
Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
Classical conditioning, also known...
Classical conditioning, also known...
1.3K
Introduction to Global Positioning System
516
The Global Positioning System (GPS) revolutionized positioning on Earth, providing precise location data through satellite ranging. The GPS system was developed in 1978 by the U.S. Department of Defense for military use, and it became available for civilian applications in 1983, transforming fields including navigation, fleet management, and time synchronization for telecommunications systems.GPS consists of satellites in medium Earth orbit, about 20,200 kilometers above the surface,...
516

