Pattern recognition receptor polymorphisms in early periodontitis

Fábio R M Leite1, Christian Enevold2, Klaus Bendtzen2

  • 1Section of Periodontology, Department of Dentistry and Oral Health, Faculty of Health Sciences, Aarhus University, Aarhus, Denmark.

Journal of Periodontology
|December 6, 2018
PubMed
Summary

Genetic variations in toll-like receptors (TLR) are linked to early periodontitis risk in adolescents. Specific single nucleotide polymorphisms (SNP) in TLR1, TLR4, TLR7, and TLR8 were associated with increased or decreased susceptibility to this inflammatory gum disease.

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